Jennifer Hom
Overview
Explore the profile of Jennifer Hom including associated specialties, affiliations and a list of published articles.
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11
Citations
843
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Recent Articles
1.
Faliti C, Van T, Anam F, Cheedarla N, Williams M, Mishra A, et al.
Nat Immunol
. 2024 Dec;
26(1):148.
PMID: 39622950
No abstract available.
2.
Faliti C, Van T, Anam F, Cheedarla N, Williams M, Mishra A, et al.
Nat Immunol
. 2024 Nov;
26(1):131-145.
PMID: 39533072
Severe acute respiratory syndrome coronavirus 2 mRNA vaccination has reduced effectiveness in certain immunocompromised individuals. However, the cellular mechanisms underlying these defects, as well as the contribution of disease-induced cellular...
3.
Woodruff M, Ramonell R, Haddad N, Anam F, Rudolph M, Walker T, et al.
Nature
. 2022 Aug;
611(7934):139-147.
PMID: 36044993
Severe SARS-CoV-2 infection has been associated with highly inflammatory immune activation since the earliest days of the COVID-19 pandemic. More recently, these responses have been associated with the emergence of...
4.
Dale G, Wilkins D, Rowley J, Scharer C, Tipton C, Hom J, et al.
J Immunol
. 2022 Apr;
208(9):2141-2153.
PMID: 35418472
The ability of the humoral immune system to generate Abs capable of specifically binding a myriad of Ags is critically dependent on the somatic hypermutation program. This program induces both...
5.
Joyner C, Ley A, Nguyen D, Ali M, Corrado A, Tipton C, et al.
Life Sci Alliance
. 2021 Dec;
5(3).
PMID: 34952892
Antibody secreting cells (ASCs) circulate after vaccination and infection and migrate to the BM where a subset known as long-lived plasma cells (LLPCs) persists and secrete antibodies for a lifetime....
6.
Woodruff M, Ramonell R, Singh Saini A, Haddad N, Anam F, Rudolph M, et al.
medRxiv
. 2020 Oct;
PMID: 33106819
An emerging feature of COVID-19 is the identification of autoreactivity in patients with severe disease that may contribute to disease pathology, however the origin and resolution of these responses remain...
7.
Sanz I, Wei C, Jenks S, Cashman K, Tipton C, Woodruff M, et al.
Front Immunol
. 2019 Nov;
10:2458.
PMID: 31681331
The increasingly recognized role of different types of B cells and plasma cells in protective and pathogenic immune responses combined with technological advances have generated a plethora of information regarding...
8.
Tipton C, Fucile C, Darce J, Chida A, Ichikawa T, Gregoretti I, et al.
Nat Immunol
. 2015 May;
16(7):755-65.
PMID: 26006014
Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells (ASCs) whose origin, diversity and contribution to serum autoantibodies remain unknown. Here, deep sequencing, proteomic profiling of autoantibodies and...
9.
Porter Jr G, Hom J, Hoffman D, Quintanilla R, Bentley K, Sheu S
Prog Pediatr Cardiol
. 2011 May;
31(2):75-81.
PMID: 21603067
Cardiac metabolism is finely tuned, and disruption of myocardial bioenergetics can be clinically devastating. Many cardiomyopathies that present early in life are due to disruption of the maturation of these...
10.
Hom J, Yu T, Yoon Y, Porter G, Sheu S
Biochim Biophys Acta
. 2010 Mar;
1797(6-7):913-21.
PMID: 20347716
Mitochondria are dynamic organelles that constantly undergo fission, fusion, and movement. Increasing evidence indicates that these dynamic changes are intricately related to mitochondrial function, suggesting that mitochondrial form and function...