Christopher M Tipton
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Explore the profile of Christopher M Tipton including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
2019
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Recent Articles
1.
Thouvenel C, Tipton C, Yamazaki Y, Zhang T, Rylaarsdam S, Hom J, et al.
J Clin Immunol
. 2025 Jan;
45(1):66.
PMID: 39812873
Reduced function or hypomorphic variants in recombination-activating genes (RAG) 1 or 2 result in a broad clinical phenotype including common variable immunodeficiency (CVID) and even adult-onset disease. Milder RAG variants...
2.
Faliti C, Van T, Anam F, Cheedarla N, Williams M, Mishra A, et al.
Nat Immunol
. 2024 Dec;
26(1):148.
PMID: 39622950
No abstract available.
3.
Faliti C, Mesina M, Choi J, Belanger S, Marshall M, Tipton C, et al.
Immunity
. 2024 Nov;
57(12):2772-2789.e8.
PMID: 39612915
During antigen-driven responses, B cells can differentiate at extra-follicular (EF) sites or initiate germinal centers (GCs) in processes that involve interactions with T cells. Here, we examined the roles of...
4.
Faliti C, Van T, Anam F, Cheedarla N, Williams M, Mishra A, et al.
Nat Immunol
. 2024 Nov;
26(1):131-145.
PMID: 39533072
Severe acute respiratory syndrome coronavirus 2 mRNA vaccination has reduced effectiveness in certain immunocompromised individuals. However, the cellular mechanisms underlying these defects, as well as the contribution of disease-induced cellular...
5.
Arends E, Zlei M, Tipton C, Cotic J, Osmani Z, de Bie F, et al.
Rheumatology (Oxford)
. 2024 May;
63(9):2387-2398.
PMID: 38775637
Objectives: Autoreactive memory B cells (MBCs) contribute to chronic and progressive courses in autoimmune diseases like SLE. The efficacy of belimumab (BEL), the first approved biologic treatment for SLE and...
6.
Chen W, Hong S, Jenks S, Anam F, Tipton C, Woodruff M, et al.
Nat Commun
. 2024 Mar;
15(1):1899.
PMID: 38429276
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple autoantibody types, some of which are produced by long-lived plasma cells (LLPC). Active SLE generates increased circulating antibody-secreting cells...
7.
Chen W, Hong S, Jenks S, Anam F, Tipton C, Woodruff M, et al.
Res Sq
. 2023 Jul;
PMID: 37461641
Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by multiple autoantibodies, some of which are present in high titers in a sustained, B cell-independent fashion consistent with their generation...
8.
Duan M, Nguyen D, Joyner C, Saney C, Tipton C, Andrews J, et al.
Cell Rep
. 2023 Jun;
42(7):112682.
PMID: 37355988
Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASCs) to long-lived plasma cells (LLPCs). We provide single-cell transcriptional resolution of 17,347 BM ASCs from...
9.
Nellore A, Zumaquero E, Scharer C, Fucile C, Tipton C, King R, et al.
Immunity
. 2023 Mar;
56(4):847-863.e8.
PMID: 36958335
Seasonal influenza vaccination elicits hemagglutinin (HA)-specific memory B (Bmem) cells, and although multiple Bmem cell populations have been characterized, considerable heterogeneity exists. We found that HA-specific human Bmem cells differed...
10.
Ramonell R, Brown M, Woodruff M, Levy J, Wise S, DelGaudio J, et al.
Mucosal Immunol
. 2023 Mar;
16(3):287-301.
PMID: 36931600
Immunoglobulin (Ig) E is central to the pathogenesis of allergic conditions, including allergic fungal rhinosinusitis. However, little is known about IgE antibody secreting cells (ASCs). We performed single-cell RNA sequencing...