Jeffrey McDonald
Overview
Explore the profile of Jeffrey McDonald including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
478
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0
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Recent Articles
1.
Zhang C, Ye M, Melikov K, Yang D, Dias do Vale G, McDonald J, et al.
Nat Commun
. 2024 Nov;
15(1):9475.
PMID: 39488519
Interorganelle contacts facilitate material exchanges and sustain the structural and functional integrity of organelles. Lipid droplets (LDs) of adipocytes are responsible for energy storage and mobilization responding to body needs....
2.
Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K
Nat Rev Mol Cell Biol
. 2024 Jul;
25(10):759-760.
PMID: 38951702
No abstract available.
3.
Salloum Z, Dauner K, Li Y, Verma N, Valdivieso-Gonzalez D, Almendro-Vedia V, et al.
Elife
. 2024 Apr;
13.
PMID: 38602170
Statins are known to be anti-inflammatory, but the mechanism remains poorly understood. Here, we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol...
4.
Zhang C, Ye M, Melikov K, Yang D, Dias do Vale G, McDonald J, et al.
bioRxiv
. 2024 Jan;
PMID: 38293096
Interorganelle contacts facilitate material exchanges and sustain the structural and functional integrity of organelles. Lipid droplets (LDs) of adipocytes are responsible for energy storage and mobilization responding to body needs....
5.
Silverberg J, Leshem Y, Calimlim B, McDonald J, Litcher-Kelly L
Curr Med Res Opin
. 2023 Sep;
39(10):1289-1296.
PMID: 37691437
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritus, skin pain, and sleep impacts, which are only reportable by patients themselves. The goal of this research...
6.
Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh H, et al.
Nat Commun
. 2023 Jul;
14(1):4101.
PMID: 37491347
Hypercholesterolemia and vascular inflammation are key interconnected contributors to the pathogenesis of atherosclerosis. How hypercholesterolemia initiates vascular inflammation is poorly understood. Here we show in male mice that hypercholesterolemia-driven endothelial...
7.
Saiioum Z, Dauner K, Li Y, Verma N, Almendro-Vedia V, Valdivieso Gonzalez D, et al.
bioRxiv
. 2023 Jan;
PMID: 36711703
Stains are known to be anti-inflammatory, but the mechanism remains poorly understood. Here we show that macrophages, either treated with statin in vitro or from statin-treated mice, have reduced cholesterol...
8.
Gao Y, McDonald J, Malinina L, Patel D, Brown R
J Lipid Res
. 2021 Nov;
63(1):100151.
PMID: 34808193
Lipid transfer proteins acquire and release their lipid cargoes by interacting transiently with source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) superfamily, the two-layer all-α-helical GLTP-fold defines proteins...
9.
Padilla B, Shields A, Taylor F, Li X, McDonald J, Green T, et al.
Orphanet J Rare Dis
. 2021 Oct;
16(1):434.
PMID: 34663404
Background: Indolent systemic mastocytosis (ISM) is a rare, clonal mast cell neoplasm characterized by severe, unpredictable symptoms. The Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF) items compose a Total Symptom...
10.
Qi X, Liu H, Thompson B, McDonald J, Zhang C, Li X
Nature
. 2019 Jun;
571(7764):279-283.
PMID: 31168089
The oncoprotein Smoothened (SMO), a G-protein-coupled receptor (GPCR) of the Frizzled-class (class-F), transduces the Hedgehog signal from the tumour suppressor Patched-1 (PTCH1) to the glioma-associated-oncogene (GLI) transcription factors, which activates...