Jeffrey M Becker
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Explore the profile of Jeffrey M Becker including associated specialties, affiliations and a list of published articles.
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76
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1078
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Recent Articles
1.
Naider F, Becker J
Molecules
. 2020 Sep;
25(18).
PMID: 32961885
Work from our laboratories over the last 35 years that has focused on Ste2p, a G protein-coupled receptor (GPCR), and its tridecapeptide ligand α-factor is reviewed. Our work utilized the...
2.
Hauser M, Abraham P, Barcelona L, Becker J
G3 (Bethesda)
. 2019 Jun;
9(8):2549-2560.
PMID: 31213515
We determined the effect on gene transcription of laser-mediated, long-wavelength UV-irradiation of by RNAseq analysis at times T15, T30, and T60 min after recovery in growth medium. Laser-irradiated cells were...
3.
Diaz-Rodriguez V, Hsu E, Ganusova E, Werst E, Becker J, Hrycyna C, et al.
Bioconjug Chem
. 2017 Dec;
29(2):316-323.
PMID: 29188996
Protein prenylation is a post-translational modification that involves the addition of one or two isoprenoid groups to the C-terminus of selected proteins using either farnesyl diphosphate or geranylgeranyl diphosphate. Three...
4.
Hauser M, Cai H, Naider F, Becker J
Bio Protoc
. 2017 Nov;
6(22).
PMID: 29104892
We describe an assay for measuring the uptake of radioactive peptides into the yeast . The methods presented here can be adapted to measure a variety of substrates transported into...
5.
Hauser M, Qian C, King S, Kauffman S, Naider F, Hettich R, et al.
J Mol Recognit
. 2017 Oct;
31(2).
PMID: 28994207
We are developing a rapid, time-resolved method using laser-activated cross-linking to capture protein-peptide interactions as a means to interrogate the interaction of serum proteins as delivery systems for peptides and...
6.
Cevheroglu O, Becker J, Son C
Biochim Biophys Acta Biomembr
. 2017 Sep;
1859(12):2435-2446.
PMID: 28958779
G protein coupled receptors bind ligands that initiate intracellular signaling cascades via heterotrimeric G proteins. In this study, involvement of the N-terminal residues of yeast G-alpha (Gpa1p) with the C-terminal...
7.
Uddin M, Naider F, Becker J
Biochim Biophys Acta Biomembr
. 2017 Jul;
1859(10):2058-2067.
PMID: 28754538
The Saccharomyces cerevisiae α-factor receptor Ste2p has been used extensively as a model to understand the molecular mechanism of signal transduction by G protein-coupled receptors (GPCRs). Single and double cysteine...
8.
Langford S, Wiggins C, Santos R, Hauser M, Becker J, Ruggles A
PLoS One
. 2017 Jul;
12(7):e0180503.
PMID: 28683074
A method for Positron Emission Particle Tracking (PEPT) based on optical feature point identification techniques is demonstrated for use in low activity tracking experiments. A population of yeast cells of...
9.
Cai H, Hauser M, Naider F, Becker J
Bio Protoc
. 2017 Jun;
6(22).
PMID: 28573166
Background: Di-/tripeptides are one of the major sources of nitrogen, carbon, and amino acids for all organisms. Synthetic peptides containing a toxic amino acid residue provide an experimental approach to...
10.
Cevheroglu O, Kumas G, Hauser M, Becker J, Son C
Biochim Biophys Acta Biomembr
. 2017 Jan;
1859(5):698-711.
PMID: 28073700
Dimerization of G protein-coupled receptors (GPCR) may play an important role in maturation, internalization, signaling and/or pharmacology of these receptors. However, the location where dimerization occurs is still under debate....