Jeffrey Krischer
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Explore the profile of Jeffrey Krischer including associated specialties, affiliations and a list of published articles.
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91
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2383
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Recent Articles
1.
Lernmark A, Agardh D, Akolkar B, Gesualdo P, Hagopian W, Haller M, et al.
Nat Rev Endocrinol
. 2024 Nov;
21(3):154-165.
PMID: 39496810
The goal of the TEDDY (The Environmental Determinants of Diabetes in the Young) study is to elucidate factors leading to the initiation of islet autoimmunity (first primary outcome) and those...
2.
Euren A, Lynch K, Lindfors K, Parikh H, Koletzko S, Liu E, et al.
Sci Rep
. 2024 Oct;
14(1):25463.
PMID: 39462122
Season of birth, viral infections, HLA haplogenotypes and non-HLA variants are implicated in the development of celiac disease and celiac disease autoimmunity, suggesting a combined role of genes and environmental...
3.
Cronholm P, Applequist J, Krischer J, Fontenot E, Davis T, Burroughs C, et al.
BMC Med Res Methodol
. 2024 Oct;
24(1):244.
PMID: 39425055
Background: Traditional medical research infrastructures relying on the Centers of Excellence (CoE) model (an infrastructure or shared facility providing high standards of research excellence and resources to advance scientific knowledge)...
4.
You L, Ferrat L, Oram R, Parikh H, Steck A, Krischer J, et al.
Diabetologia
. 2024 Aug;
67(11):2507-2517.
PMID: 39103721
Aims/hypothesis: Although statistical models for predicting type 1 diabetes risk have been developed, approaches that reveal the heterogeneity of the at-risk population by identifying clinically meaningful clusters are lacking. We...
5.
Jonsdottir B, Clasen J, Vehik K, Lernmark A, Lundgren M, Bonifacio E, et al.
J Clin Endocrinol Metab
. 2024 Jul;
110(2):498-510.
PMID: 38996042
Context: Autoantibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) define preclinical autoimmune thyroid disease (AITD), which can progress to either clinical hypothyroidism or hyperthyroidism. Objective: We determined the age at...
6.
Singh T, Weiss A, Vehik K, Krischer J, Rewers M, Toppari J, et al.
Diabetologia
. 2024 May;
67(8):1582-1587.
PMID: 38819466
Aims/hypothesis: Delivery by Caesarean section continues to rise globally and has been associated with the risk of developing type 1 diabetes and the rate of progression from pre-symptomatic stage 1...
7.
Meng G, Pan Y, Tang W, Zhang L, Cui Y, Schumacher F, et al.
Genome Med
. 2024 Apr;
16(1):65.
PMID: 38685057
Using computational tools, bulk transcriptomics can be deconvoluted to estimate the abundance of constituent cell types. However, existing deconvolution methods are conditioned on the assumption that the whole study population...
8.
You L, Liu X, Krischer J
Stat Med
. 2024 Apr;
43(12):2452-2471.
PMID: 38599784
Many longitudinal studies are designed to monitor participants for major events related to the progression of diseases. Data arising from such longitudinal studies are usually subject to interval censoring since...
9.
Arumugam P, Carey B, Wikenheiser-Brokamp K, Krischer J, Wessendarp M, Shima K, et al.
Mol Ther Methods Clin Dev
. 2024 Apr;
32(2):101213.
PMID: 38596536
Pulmonary macrophage transplantation (PMT) is a gene and cell transplantation approach in development as therapy for hereditary pulmonary alveolar proteinosis (hPAP), a surfactant accumulation disorder caused by mutations in (and...
10.
You L, Ferrat L, Oram R, Parikh H, Steck A, Krischer J, et al.
medRxiv
. 2023 Oct;
PMID: 37873281
Background: Although statistical models for predicting type 1 diabetes risk have been developed, approaches that reveal clinically meaningful clusters in the at-risk population and allow for non-linear relationships between predictors...