Jorma Toppari
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Explore the profile of Jorma Toppari including associated specialties, affiliations and a list of published articles.
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424
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Recent Articles
1.
Calhoun P, Spanbauer C, Steck A, Frohnert B, Herman M, Keymeulen B, et al.
Diabetologia
. 2025 Feb;
PMID: 39934369
Aims/hypothesis: We aimed to assess whether continuous glucose monitor (CGM) metrics can accurately predict stage 3 type 1 diabetes diagnosis in those with islet autoantibodies (AAb). Methods: Baseline CGM data...
2.
Lernmark A, Agardh D, Akolkar B, Gesualdo P, Hagopian W, Haller M, et al.
Nat Rev Endocrinol
. 2024 Nov;
21(3):154-165.
PMID: 39496810
The goal of the TEDDY (The Environmental Determinants of Diabetes in the Young) study is to elucidate factors leading to the initiation of islet autoimmunity (first primary outcome) and those...
3.
Euren A, Lynch K, Lindfors K, Parikh H, Koletzko S, Liu E, et al.
Sci Rep
. 2024 Oct;
14(1):25463.
PMID: 39462122
Season of birth, viral infections, HLA haplogenotypes and non-HLA variants are implicated in the development of celiac disease and celiac disease autoimmunity, suggesting a combined role of genes and environmental...
4.
Eggert A, Laasanen S, Nurmio M, Wahlgren A, Jahnukainen K, Eerola K, et al.
Andrology
. 2024 Oct;
PMID: 39422608
Background: Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has...
5.
Virtanen S, Peltonen E, Hakola L, Niinisto S, Takkinen H, Ahonen S, et al.
J Nutr
. 2024 Sep;
154(11):3465-3474.
PMID: 39313195
Background: Prospective longitudinal evidence considering the entire childhood food consumption in relation to the development of islet autoimmunity (IA or) type 1 diabetes is lacking. Objectives: We studied the associations...
6.
Ojwang V, Nwaru B, Hanna-Mari T, Heli T, Kaila M, Ahonen S, et al.
Pediatr Allergy Immunol
. 2024 Sep;
35(9):e14240.
PMID: 39282918
Background: Association of early pregnancy body mass index (BMI) and maternal gestational weight gain (GWG), and asthma and allergic disease in children is unclear. Methods: We analyzed data from 3176...
7.
8.
Ekman I, Schroderus A, Vuorinen T, Knip M, Veijola R, Toppari J, et al.
Clin Immunol
. 2024 Jul;
266:110330.
PMID: 39067678
Cytomegalovirus (CMV) infection has a life-long impact on the immune system, particularly on memory T cells. However, the effect of early life CMV infection on the phenotype and functionality of...
9.
Pulawska-Moon K, Ponikwicka-Tyszko D, Lebiedzinska W, Pilaszewicz-Puza A, Bernaczyk P, Koda M, et al.
Int J Cancer
. 2024 Jul;
155(10):1846-1857.
PMID: 39039845
Zona pellucida 3 (ZP3) expression is classically found in the ZP-layer of the oocytes, lately shown in ovarian and prostate cancer. A successful ZP3 ovarian cancer immunotherapy in transgenic mice...
10.
Jonsdottir B, Clasen J, Vehik K, Lernmark A, Lundgren M, Bonifacio E, et al.
J Clin Endocrinol Metab
. 2024 Jul;
110(2):498-510.
PMID: 38996042
Context: Autoantibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) define preclinical autoimmune thyroid disease (AITD), which can progress to either clinical hypothyroidism or hyperthyroidism. Objective: We determined the age at...