Jeffrey J Molldrem
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Explore the profile of Jeffrey J Molldrem including associated specialties, affiliations and a list of published articles.
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98
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3398
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Recent Articles
1.
Kannan S, Vedia R, Molldrem J
Front Immunol
. 2024 Oct;
15:1419807.
PMID: 39355256
This mini review summarizes the immunobiology of myelodysplastic syndromes, specifically focusing on the interactions between immune cells, cytokines, and dysplastic cells within the tumor microenvironment in the bone marrow. We...
2.
Hayase E, Hayase T, Mukherjee A, Stinson S, Jamal M, Ortega M, et al.
Cell Host Microbe
. 2024 Aug;
32(9):1621-1636.e6.
PMID: 39214085
Acute lower gastrointestinal GVHD (aLGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation. Although the intestinal microbiota is associated with the incidence of aLGI-GVHD, how the intestinal microbiota...
3.
He H, Vedia R, Lu S, Li Q, Cox K, St John L, et al.
Cytotherapy
. 2024 Jul;
26(11):1331-1340.
PMID: 39033444
Background Aims: Hu8F4 is a T-cell receptor-like antibody with high affinity for the leukemia-associated antigen PR1/HLA-A2 epitope. Adapted into a chimeric antigen receptor (CAR) format, Hu8F4-CAR is composed of the...
4.
Boda A, Liu A, Castro-Pando S, Whitfield B, Molldrem J, Al-Atrash G, et al.
Cancer Res Commun
. 2024 Mar;
4(3):911-918.
PMID: 38477596
Significance: We find that AML acquires resistance to innate immune activation via the STING pathway through aberrant splicing of the STING transcript including two novel forms described herein that act...
5.
Jin Y, Miyama T, Brown A, Hayase T, Song X, Singh A, et al.
Cancer Immunol Res
. 2024 Feb;
12(5):530-543.
PMID: 38363296
Tools for genome-wide rapid identification of peptide-major histocompatibility complex targets of T-cell receptors (TCR) are not yet universally available. We present a new antigen screening method, the T-synapse (Tsyn) reporter...
6.
Tian Z, Shi C, Yang G, Allen J, Shi Q, Al-Shami A, et al.
Leukemia
. 2023 Nov;
38(1):226.
PMID: 38036631
No abstract available.
7.
Tian Z, Shi C, Yang G, Allen J, Shi Q, Al-Shami A, et al.
Leukemia
. 2023 Aug;
37(10):2006-2016.
PMID: 37634013
Patients harboring CRLF2-rearranged B-lineage acute lymphocytic leukemia (B-ALL) face a 5-year survival rate as low as 20%. While significant gains have been made to position targeted therapies for B-ALL treatment,...
8.
Sizova O, St John L, Ma Q, Molldrem J
Front Immunol
. 2023 Apr;
14:1166189.
PMID: 37020553
Graft versus host disease (GVHD) represents the major complication after allogeneic hematopoietic stem cell transplantation (Allo-SCT). GVHD-prone patients rely on GVHD prophylaxis (e.g. methotrexate) and generalized anti-GVHD medical regimen (glucocorticoids)....
9.
Lee S, Wang F, Grefe M, Trujillo-Ocampo A, Ruiz-Vasquez W, Takahashi K, et al.
Clin Cancer Res
. 2023 Mar;
29(10):1938-1951.
PMID: 36988276
Purpose: The aim of this study is to determine immune-related biomarkers to predict effective antitumor immunity in myelodysplastic syndrome (MDS) during immunotherapy (IMT, αCTLA-4, and/or αPD-1 antibodies) and/or hypomethylating agent...
10.
Hayase E, Hayase T, Mukherjee A, Stinson S, Jamal M, Ortega M, et al.
Res Sq
. 2023 Feb;
PMID: 36778495
Acute gastrointestinal intestinal GVHD (aGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation, and the intestinal microbiota is known to impact on its severity. However, an association between...