Jeffrey J Molldrem
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Explore the profile of Jeffrey J Molldrem including associated specialties, affiliations and a list of published articles.
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98
Citations
3398
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Recent Articles
11.
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment
Schwabkey Z, Wiesnoski D, Chang C, Tsai W, Pham D, Ahmed S, et al.
Sci Transl Med
. 2022 Nov;
14(671):eabo3445.
PMID: 36383683
Not all patients with cancer and severe neutropenia develop fever, and the fecal microbiome may play a role. In a single-center study of patients undergoing hematopoietic cell transplant ( = ...
12.
Hayase E, Hayase T, Jamal M, Miyama T, Chang C, Ortega M, et al.
Cell
. 2022 Sep;
185(20):3705-3719.e14.
PMID: 36179667
The intestinal microbiota is an important modulator of graft-versus-host disease (GVHD), which often complicates allogeneic hematopoietic stem cell transplantation (allo-HSCT). Broad-spectrum antibiotics such as carbapenems increase the risk for intestinal...
13.
Lee S, Wang F, Trujillo-Ocampo A, Ruiz-Vasquez W, Cho H, Takahashi K, et al.
EJHaem
. 2022 Jul;
1(2):552-557.
PMID: 35844984
The aim of this study is to investigate whether the peripheral blood (PB) can serve as a surrogate immune-microenvironment to bone marrow for genetic and immune monitoring in myelodysplastic syndrome...
14.
Lu S, Tallis E, Ding X, Li D, Cox K, You M, et al.
Cytotherapy
. 2021 Jul;
23(9):793-798.
PMID: 34215503
Background Aims: Human myeloperoxidase has been shown to be overexpressed in many types of leukemia, such as chronic myeloid leukemia, acute myeloid leukemia and myelodysplastic syndrome. The authors identified two...
15.
He H, Kondo Y, Ishiyama K, Alatrash G, Lu S, Cox K, et al.
Leukemia
. 2020 Jan;
34(6):1626-1636.
PMID: 31908357
Immunotherapy targeting leukemia-associated antigens has shown promising results. Because of the heterogeneity of leukemia, vaccines with a single peptide have elicited only a limited immune response. Targeting several peptides together...
16.
Mehta R, Bassett R, Olson A, Chen J, Ahmed S, Alousi A, et al.
Haematologica
. 2019 Apr;
104(12):e555-e557.
PMID: 30948491
No abstract available.
17.
Nahas M, Stroopinsky D, Rosenblatt J, Cole L, Pyzer A, Anastasiadou E, et al.
Br J Haematol
. 2019 Mar;
185(4):679-690.
PMID: 30828801
Acute myeloid leukaemia (AML) is a lethal haematological malignancy characterized by an immunosuppressive milieu in the tumour microenvironment (TME) that fosters disease growth and therapeutic resistance. Hypomethylating agents (HMAs) demonstrate...
18.
Chamoun K, Milton D, Ledesma C, Young K, Jabbour E, Alatrash G, et al.
Biol Blood Marrow Transplant
. 2019 Mar;
25(7):1347-1354.
PMID: 30826465
Although bortezomib and rituximab have synergistic activity in patients with lymphoma and both can attenuate graft-versus-host disease (GVHD), the drugs have not been used together in patients undergoing allogeneic stem...
19.
Herrmann A, Im J, Pareek S, Ruiz-Vasquez W, Lu S, Sergeeva A, et al.
Front Immunol
. 2019 Feb;
9:3153.
PMID: 30713535
Despite substantial advances in the treatment of acute myeloid leukemia (AML), only 30% of patients survive more than 5 years. Therefore, new therapeutics are much needed. Here, we present a...
20.
Capello M, Vykoukal J, Katayama H, Bantis L, Wang H, Kundnani D, et al.
Nat Commun
. 2019 Jan;
10(1):254.
PMID: 30651550
Although B cell response is frequently found in cancer, there is little evidence that it alters tumor development or progression. The process through which tumor-associated antigens trigger humoral response is...