Jeff Hsu
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Explore the profile of Jeff Hsu including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
1428
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0
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Recent Articles
1.
Hsu J, Chong C, Serrill J, Goon L, Balayan J, Johnson E, et al.
Mol Cancer Ther
. 2022 Nov;
22(2):179-191.
PMID: 36399631
The multi-receptor tyrosine kinase inhibitor XL092 has been developed to inhibit the activity of oncogenic targets, including MET, VEGFR2, and the TAM family of kinases TYRO3, AXL and MER. Presented...
2.
Treff N, Zimmerman R, Bechor E, Hsu J, Rana B, Jensen J, et al.
Eur J Med Genet
. 2019 Apr;
62(8):103647.
PMID: 31026593
Preimplantation genetic testing (PGT) has been successfully applied to reduce the risk of miscarriage, improve IVF success rates, and prevent inheritance of monogenic disease and unbalanced translocations. The present study...
3.
Reilley M, McCoon P, Cook C, Lyne P, Kurzrock R, Kim Y, et al.
J Immunother Cancer
. 2018 Nov;
6(1):119.
PMID: 30446007
Background: The Janus kinase (JAK) and signal transduction and activation of transcription (STAT) signaling pathway is an attractive target in multiple cancers. Activation of the JAK-STAT pathway is important in...
4.
Deutsch E, Cohen-Jonathan Moyal E, Gregorc V, Zucali P, Menard J, Soria J, et al.
Oncotarget
. 2017 Sep;
8(34):56199-56209.
PMID: 28915584
Current treatments for advanced solid tumors tend to be only palliative. Although radiotherapy is administered with a curative intent, radioresistance and dose-limiting toxicities pose limitations to treatment. Abexinostat, an oral...
5.
Kuo H, Ezell S, Hsieh S, Schweighofer K, Cheung L, Wu S, et al.
Am J Cancer Res
. 2016 Dec;
6(11):2489-2501.
PMID: 27904766
Diffuse large B cell lymphoma (DLBCL) is a heterogeneous lymphoma and the most common subtype of non-Hodgkin lymphoma, accounting for roughly 30% of newly diagnosed cases in the United States....
6.
Hong D, Kurzrock R, Kim Y, Woessner R, Younes A, Nemunaitis J, et al.
Sci Transl Med
. 2015 Nov;
7(314):314ra185.
PMID: 26582900
Next-generation sequencing technologies have greatly expanded our understanding of cancer genetics. Antisense technology is an attractive platform with the potential to translate these advances into improved cancer therapeutics, because antisense...
7.
Huang L, Damle S, Booten S, Singh P, Sabripour M, Hsu J, et al.
PLoS One
. 2015 Jul;
10(7):e0132798.
PMID: 26207833
Liver regeneration after partial hepatectomy (PHx) is a complex and well-orchestrated biological process in which synchronized cell proliferation is induced in response to the loss of liver mass. To define...
8.
Gutschner T, Hammerle M, Eissmann M, Hsu J, Kim Y, Hung G, et al.
Cancer Res
. 2012 Dec;
73(3):1180-9.
PMID: 23243023
The long noncoding RNA MALAT1 (metastasis-associated lung adenocarcinoma transcript 1), also known as MALAT-1 or NEAT2 (nuclear-enriched abundant transcript 2), is a highly conserved nuclear noncoding RNA (ncRNA) and a...
9.
To M, Quigley D, Mao J, Del Rosario R, Hsu J, Hodgson G, et al.
Mol Cancer Res
. 2011 Aug;
9(10):1339-45.
PMID: 21807965
Alterations in DNA copy number contribute to the development and progression of cancers and are common in epithelial tumors. We have used array Comparative Genomic Hybridization (aCGH) to visualize DNA...
10.
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice
To M, Perez-Losada J, Mao J, Hsu J, Jacks T, Balmain A
Nat Genet
. 2006 Jul;
38(8):926-30.
PMID: 16823377
Pulmonary adenoma susceptibility 1 (Pas1) is the major mouse lung cancer susceptibility locus on chromosome 6 (ref. 1). Kras2 is a common target of somatic mutation in chemically induced mouse...