Jef Willems
Overview
Explore the profile of Jef Willems including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
159
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0
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Recent Articles
1.
Wosten-van Asperen R, la Roi-Teeuw H, Tissing W, Jordan I, Dohna-Schwake C, Bottari G, et al.
Pediatr Crit Care Med
. 2025 Feb;
26(2):e177-e185.
PMID: 39982155
Objectives: The Pediatric Sepsis Definition Task Force developed and validated a new organ dysfunction score, the Phoenix Sepsis Score (PSS), as a predictor of mortality in children with suspected or...
2.
Caorsi R, Consolaro A, Speziani C, Sozeri B, Ulu K, Faugier-Fuentes E, et al.
J Autoimmun
. 2024 Jun;
147:103265.
PMID: 38838452
Objectives: The aim of the study was to establish an international multicenter registry to collect data on patients with Multisystem Inflammatory Syndrome in Children (MIS-C), in order to highlight a...
3.
Willems J, Heyndrickx A, Schelstraete P, Gadeyne B, De Cock P, Vandendriessche S, et al.
Sci Rep
. 2024 Jan;
14(1):1657.
PMID: 38238516
Prospective audit with feedback during infectious diseases ward rounds (IDWR) is a common antimicrobial stewardship (AMS) practice on the Paediatric Intensive Care Unit (PICU). These interdisciplinary meetings rely on the...
4.
Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children
Dhont E, Van Der Heggen T, Snauwaert E, Willems J, Croubels S, Delanghe J, et al.
Pediatr Nephrol
. 2023 Nov;
39(5):1607-1616.
PMID: 37994980
Background: Augmented renal clearance (ARC) holds a risk of subtherapeutic drug concentrations. Knowledge of patient-, disease-, and therapy-related factors associated with ARC would allow predicting which patients would benefit from...
5.
Wosten-van Asperen R, la Roi-Teeuw H, van Amstel R, Bos L, Tissing W, Jordan I, et al.
EClinicalMedicine
. 2023 Oct;
65:102252.
PMID: 37842550
Background: Identifying phenotypes in sepsis patients may enable precision medicine approaches. However, the generalisability of these phenotypes to specific patient populations is unclear. Given that paediatric cancer patients with sepsis...
6.
Martens T, Schaballie H, Willekens J, Schelstraete P, Willems J, Muthialu N, et al.
JTCVS Tech
. 2023 Feb;
17:159-163.
PMID: 36820339
Objectives: Congenital tracheomalacia can be the cause of respiratory failure in young children. Although the indication for surgical treatment has already been discussed vigorously, no clear guidelines about the modality...
7.
Nielsen J, Agbeko R, Bate J, Jordan I, Dohna-Schwake C, Potratz J, et al.
Front Pediatr
. 2022 Dec;
10:1024273.
PMID: 36533247
Background: Intensified treatment protocols have improved survival of pediatric oncology patients. However, these treatment protocols are associated with increased treatment-related morbidity requiring admission to pediatric intensive care unit (PICU). We...
8.
Van Der Heggen T, Dhont E, Willems J, Herck I, Delanghe J, Stove V, et al.
Pediatr Crit Care Med
. 2022 Apr;
23(7):e309-e318.
PMID: 35426861
Objectives: In critically ill children, severely altered pharmacokinetics may result in subtherapeutic β-lactam antibiotic concentrations when standard pediatric dosing regimens are applied. However, it remains unclear how to recognize patients...
9.
Slooff V, Hoogendoorn R, Nielsen J, Pappachan J, Amigoni A, Caramelli F, et al.
Ann Intensive Care
. 2022 Jan;
12(1):8.
PMID: 35092500
Background: The use of extracorporeal membrane oxygenation (ECMO) in pediatric patients with underlying malignancies remains controversial. However, in an era in which the survival rates for children with malignancies have...
10.
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, et al.
J Exp Med
. 2021 Dec;
219(2).
PMID: 34914824
In rare instances, pediatric SARS-CoV-2 infection results in a novel immunodysregulation syndrome termed multisystem inflammatory syndrome in children (MIS-C). We compared MIS-C immunopathology with severe COVID-19 in adults. MIS-C does...