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Christian Dohna-Schwake

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Articles 81
Citations 564
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Recent Articles
1.
Wosten-van Asperen R, la Roi-Teeuw H, Tissing W, Jordan I, Dohna-Schwake C, Bottari G, et al.
Pediatr Crit Care Med . 2025 Feb; 26(2):e177-e185. PMID: 39982155
Objectives: The Pediatric Sepsis Definition Task Force developed and validated a new organ dysfunction score, the Phoenix Sepsis Score (PSS), as a predictor of mortality in children with suspected or...
2.
Schwarz S, Denis L, Nedoschill E, Buehler A, Danko V, Hilger A, et al.
Adv Sci (Weinh) . 2025 Feb; :e2415235. PMID: 39899647
During the first days of neonatal growth, the central nervous system (CNS) develops self-regulatory mechanisms to ensure constant cerebral perfusion. However, this vascular neogenesis takes place at a microscopic scale...
3.
Hojeij R, Brensing P, Nonnemacher M, Kowall B, Felderhoff-Muser U, Dudda M, et al.
J Clin Epidemiol . 2024 Dec; 178:111634. PMID: 39647538
Objectives: The performance of injury severity scores (ISSs), used widely to quantify injury severity and predict outcomes, has not been investigated in German pediatric cases. This study aims to identify...
4.
Garcia-Farina B, Rink L, Santarini V, Westkemper M, Dohna-Schwake C, Mohlendick B
Front Pharmacol . 2024 Nov; 15:1477755. PMID: 39508042
Background And Aims: A number of case reports have documented the occurrence of acute hepatic and renal toxicity during treatment with deferasirox (DFX). The precise mechanisms underlying these adverse events...
5.
Diexer S, Ihling A, Gomes D, Moritz S, Simon A, Dohna-Schwake C, et al.
Trials . 2024 Oct; 25(1):678. PMID: 39402608
Background: Overuse and misuse of antibiotics is one of the driving factors of antimicrobial resistance, a growing global health threat. The use of antibiotics is particularly high in children. Even...
6.
Bruns N, Hauschild J, Lainka E, Dohna-Schwake C
Pediatr Transplant . 2024 Jul; 28(5):e14830. PMID: 39030994
Background: In spite of improved survival rates after pediatric liver transplantation, infections remain major contributors to perioperative morbidity and mortality. This study aimed to understand the impact of type and...
7.
Bruns N, Feddahi N, Hojeij R, Rossi R, Dohna-Schwake C, Stein A, et al.
Resuscitation . 2024 Jul; 202:110309. PMID: 39002696
Importance: In neonates with birth asphyxia (BA) and hypoxic-ischemic encephalopathy, therapeutic hypothermia (TH), initiated within six hours, is the only safe and established neuroprotective measure to prevent secondary brain injury....
8.
Paul L, Greve S, Hegemann J, Gienger S, Loffelhardt V, Marina A, et al.
Front Neurosci . 2024 Jun; 18:1411151. PMID: 38903601
Background And Objectives: Amplitude-integrated EEG (aEEG) is used to assess electrocortical activity in pediatric intensive care if (continuous) full channel EEG is unavailable but evidence regarding the meaning of suppressed...
9.
Bruns N, Joist C, Joist C, Daniels A, Felderhoff-Muser U, Dohna-Schwake C, et al.
J Clin Med . 2024 Apr; 13(5). PMID: 38592307
Precise assessment of hypnotic depth in children during procedural sedation with preserved spontaneous breathing is challenging. The Narcotrendindex (NI) offers uninterrupted information by continuous electrocortical monitoring without the need to...
10.
Lu K, Bruns N, Pentek C, Marina A, Gangfuss A, Kolbel H, et al.
Pediatr Infect Dis J . 2024 Mar; 43(6):e214-e217. PMID: 38451881
The European Society for Clinical Microbiology and Infectious Diseases recommends 3rd generation cephalosporins and metronidazole for empirical treatment of community-acquired brain abscesses. In 53 retrospectively analyzed pediatric patients with community-acquired...