Jean Pierre Le Couedic
Overview
Explore the profile of Jean Pierre Le Couedic including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
232
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Recent Articles
1.
Cabagnols X, Favale F, Pasquier F, Messaoudi K, Defour J, Ianotto J, et al.
Blood
. 2015 Oct;
127(3):333-42.
PMID: 26450985
Mutations in signaling molecules of the cytokine receptor axis play a central role in myeloproliferative neoplasm (MPN) pathogenesis. Polycythemia vera is mainly related to JAK2 mutations, whereas a wider mutational...
2.
Chaligne R, James C, Tonetti C, Besancenot R, Le Couedic J, Fava F, et al.
Blood
. 2007 Aug;
110(10):3735-43.
PMID: 17709604
The MPL (W515L and W515K) mutations have been detected in granulocytes of patients suffering from certain types of primitive myelofibrosis (PMF). It is still unknown whether this molecular event is...
3.
Dupont S, Masse A, James C, Teyssandier I, Lecluse Y, Larbret F, et al.
Blood
. 2007 Mar;
110(3):1013-21.
PMID: 17389763
The JAK2 617V>F mutation is frequent in polycythemia vera (PV) and essential thrombocythemia (ET). Using quantitative polymerase chain reaction (PCR), we found that high levels of JAK2 617V>F in PV...
4.
Raslova H, Komura E, Le Couedic J, Larbret F, Debili N, Feunteun J, et al.
J Clin Invest
. 2004 Jul;
114(1):77-84.
PMID: 15232614
Paris-Trousseau syndrome (PTS; also known as Jacobsen syndrome) is characterized by several congenital anomalies including a dysmegakaryopoiesis with two morphologically distinct populations of megakaryocytes (MKs). PTS patients harbor deletions on...
5.
Raslova H, Roy L, Vourch C, Le Couedic J, Brison O, Metivier D, et al.
Blood
. 2002 Oct;
101(2):541-4.
PMID: 12393414
It is believed that polyploidy induces an orchestrated increase in gene expression. To know whether all alleles remain functional during megakaryocyte polyploidization, we used a well-established fluorescence in situ hybridization...