Frederic Larbret
Overview
Explore the profile of Frederic Larbret including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1008
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0
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Recent Articles
1.
Garcia-Sanchez J, Bonnet E, Loubatier C, Doye A, Paillier G, Segui F, et al.
iScience
. 2025 Feb;
28(2):111838.
PMID: 39995862
Transcription factor EB (TFEB) is a key transcription factor that orchestrates the cellular response to stress. Dysregulation of TFEB is associated with a range of human diseases, and understanding the...
2.
Billaud M, Larbret F, Czerucka D
Front Immunol
. 2023 Dec;
14:1292410.
PMID: 38077367
Climate change is increasing ocean temperatures and consequently impacts marine life (e.g., bacterial communities). In this context, studying host-pathogen interactions in marine organisms is becoming increasingly important, not only for...
3.
Tiroille V, Krug A, Bokobza E, Kahi M, Bulcaen M, Ensinck M, et al.
Mol Ther Nucleic Acids
. 2023 Jul;
33:57-74.
PMID: 37435135
Genome engineering has become more accessible thanks to the CRISPR-Cas9 gene-editing system. However, using this technology in synthetic organs called "organoids" is still very inefficient. This is due to the...
4.
Diazzi S, Baeri A, Fassy J, Lecacheur M, Marin-Bejar O, Girard C, et al.
EMBO Mol Med
. 2022 Feb;
14(3):e15295.
PMID: 35156321
Lineage dedifferentiation toward a mesenchymal-like state displaying myofibroblast and fibrotic features is a common mechanism of adaptive and acquired resistance to targeted therapy in melanoma. Here, we show that the...
5.
Larbret F, Biber P, Dubois N, Ivanov S, Lafanechere L, Tartare-Deckert S, et al.
Front Pharmacol
. 2022 Jan;
12:778216.
PMID: 35069199
Actin networks are dynamically regulated through constant depolymerization and polymerization cycles. Although the fundamental mechanisms that govern these processes have been identified, the nature and role of post-translational modifications (PTMs)...
6.
Berestjuk I, Lecacheur M, Carminati A, Diazzi S, Rovera C, Prodhomme V, et al.
EMBO Mol Med
. 2021 Dec;
14(2):e11814.
PMID: 34957688
Resistance to BRAF/MEK inhibitor therapy in BRAF -mutated advanced melanoma remains a major obstacle that limits patient benefit. Microenvironment components including the extracellular matrix (ECM) can support tumor cell adaptation...
7.
Luci C, Vieira E, Bourinet M, Rousseau D, Bonnafous S, Patouraux S, et al.
Cell Mol Gastroenterol Hepatol
. 2021 Aug;
13(1):173-191.
PMID: 34411785
Background & Aims: Spleen tyrosine kinase (SYK) signaling pathway regulates critical processes in innate immunity, but its role in parenchymal cells remains elusive in chronic liver diseases. We investigate the...
8.
Girard C, Lecacheur M, Ben Jouira R, Berestjuk I, Diazzi S, Prodhomme V, et al.
Cancer Res
. 2020 Mar;
80(10):1927-1941.
PMID: 32179513
Aberrant extracellular matrix (ECM) deposition and stiffening is a physical hallmark of several solid cancers and is associated with therapy failure. BRAF-mutant melanomas treated with BRAF and MEK inhibitors almost...
9.
Ibanez L, Pontier-Bres R, Larbret F, Rekima A, Verhasselt V, Blin-Wakkach C, et al.
Front Immunol
. 2019 Apr;
10:643.
PMID: 31001263
Intestinal mononuclear phagocytes (MPs) comprise dendritic cells (DCs) and macrophages (Mφs) that play different roles in response to infection. After phagocytosis, DCs expressing CD103 transport from the intestinal tract to...
10.
Mothe-Satney I, Murdaca J, Sibille B, Rousseau A, Squillace R, Le Menn G, et al.
Sci Rep
. 2016 Sep;
6:34317.
PMID: 27680392
Metabolism plays an important role in T cell biology and changes in metabolism drive T cell differentiation and fate. Most research on the role of metabolism in T lymphocytes focuses...