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Jean Feunteun

Explore the profile of Jean Feunteun including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 1342
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Recent Articles
1.
Pradeu T, Daignan-Fornier B, Ewald A, Germain P, Okasha S, Plutynski A, et al.
Biol Rev Camb Philos Soc . 2023 May; 98(5):1668-1686. PMID: 37157910
Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research...
2.
Feunteun J, Ostyn P, Delaloge S
iScience . 2022 May; 25(5):104217. PMID: 35494254
Since the discovery of oncogenes and tumor suppressor genes in the late past century, cancer research has been overwhelmingly focused on the genetics and biology of tumor cells and hence...
3.
Miran I, Scherer D, Ostyn P, Mazouni C, Drusch F, Bernard M, et al.
Front Oncol . 2020 Sep; 10:1506. PMID: 32974182
The tissue stroma plays a major role in tumors' natural history. Most programs for tumor progression are not activated as cell-autonomous processes but under the conditions of cross-talks between tumor...
4.
Petitalot A, Dardillac E, Jacquet E, Nhiri N, Guirouilh-Barbat J, Julien P, et al.
Mol Cancer Res . 2018 Sep; 17(1):54-69. PMID: 30257991
mutations have been identified that increase the risk of developing hereditary breast and ovarian cancers. Genetic screening is now offered to patients with a family history of cancer, to adapt...
5.
Hennig K, Antignac J, Bichon E, Morvan M, Miran I, Delaloge S, et al.
Anal Bioanal Chem . 2017 Nov; 410(1):259-275. PMID: 29147745
Body mass index is a known breast cancer risk factor due to, among other mechanisms, adipose-derived hormones. We developed a method for steroid hormone profiling in adipose tissue to evaluate...
6.
Jouenne F, Chauvot de Beauchene I, Bollaert E, Avril M, Caron O, Ingster O, et al.
J Med Genet . 2017 Jun; 54(9):607-612. PMID: 28592523
Background: Sarcomas are rare mesenchymal malignancies whose pathogenesis is poorly understood; both environmental and genetic risk factors could contribute to their aetiology. Methods And Results: We performed whole-exome sequencing (WES)...
7.
van Kempen L, Redpath M, Elchebly M, Klein K, Papadakis A, Wilmott J, et al.
Sci Transl Med . 2016 Dec; 8(369):369ra177. PMID: 27974665
Male gender is independently and significantly associated with poor prognosis in melanoma of all clinical stages. The biological underpinnings of this sex difference remain largely unknown, but we hypothesized that...
8.
Wang H, Bierie B, Li A, Pathania S, Toomire K, Dimitrov S, et al.
Mol Cell . 2016 Jul; 63(2):277-292. PMID: 27373334
An abnormal differentiation state is common in BRCA1-deficient mammary epithelial cells, but the underlying mechanism is unclear. Here, we report a convergence between DNA repair and normal, cultured human mammary...
9.
Communal L, Vilasco M, Hugon-Rodin J, Courtin A, Mourra N, Lahlou N, et al.
Oncotarget . 2016 Jun; 7(29):45317-45330. PMID: 27246982
Women with inherited BRCA1 mutations have an elevated risk (40-80%) for developing breast and ovarian cancers. Reproductive history has been reported to alter this risk, suggesting a relationship between ovarian...
10.
Lakisic G, Lebreton A, Pourpre R, Wendling O, Libertini E, Radford E, et al.
PLoS Genet . 2016 Mar; 12(3):e1005898. PMID: 26938916
BAHD1 is a vertebrate protein that promotes heterochromatin formation and gene repression in association with several epigenetic regulators. However, its physiological roles remain unknown. Here, we demonstrate that ablation of...