Jaswir Basran
Overview
Explore the profile of Jaswir Basran including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
62
Citations
1013
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kwon H, Basran J, Pathak C, Hussain M, Freeman S, Fielding A, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
133(26):14699-14706.
PMID: 38505375
Oxygen activation in all heme enzymes requires the formation of high oxidation states of iron, usually referred to as ferryl heme. There are two known intermediates: Compound I and Compound...
2.
Ward J, Romartinez-Alonso B, Kay D, Bellamy-Carter J, Thurairajah B, Basran J, et al.
J Biol Chem
. 2024 Jan;
300(2):105651.
PMID: 38237679
Mouse Double Minute 2 (MDM2) is a key negative regulator of the tumor suppressor protein p53. MDM2 overexpression occurs in many types of cancer and results in the suppression of...
3.
Burton M, Cresser-Brown J, Thomas M, Portolano N, Basran J, Freeman S, et al.
J Biol Chem
. 2022 Mar;
298(3):101754.
PMID: 35247676
No abstract available.
4.
Falcicchio M, Ward J, Chothia S, Basran J, Mohindra A, Macip S, et al.
Chem Sci
. 2021 Nov;
12(39):12985-12992.
PMID: 34745529
14-3-3 proteins are an important family of hub proteins that play important roles in many cellular processes a large network of interactions with partner proteins. Many of these protein-protein interactions...
5.
Basran J, Booth E, Campbell L, Thackray S, Jesani M, Clayden J, et al.
J Inorg Biochem
. 2021 Sep;
225:111604.
PMID: 34571402
The kynurenine pathway is the major route of tryptophan metabolism. The first step of this pathway is catalysed by one of two heme-dependent dioxygenase enzymes - tryptophan 2,3-dioxygenase (TDO) and...
6.
Bellamy-Carter J, Mohata M, Falcicchio M, Basran J, Higuchi Y, Doveston R, et al.
Chem Sci
. 2021 Aug;
12(32):10724-10731.
PMID: 34447561
Protein-protein interactions (PPIs) are key therapeutic targets. Most PPI-targeting drugs in the clinic inhibit these important interactions; however, stabilising PPIs is an attractive alternative in cases where a PPI is...
7.
Chen X, Chothia S, Basran J, Hopkinson R
Chem Commun (Camb)
. 2021 May;
57(47):5778-5781.
PMID: 33997872
Tetrahydrofolic acid and formaldehyde are key human metabolites but their physiologically relevant chemistry is undefined. Our NMR studies confirm formaldehyde as a product of tetrahydrofolic acid degradation but also reveal...
8.
Kwon H, Basran J, Pathak C, Hussain M, Freeman S, Fielding A, et al.
Angew Chem Int Ed Engl
. 2021 Apr;
60(26):14578-14585.
PMID: 33826799
Oxygen activation in all heme enzymes requires the formation of high oxidation states of iron, usually referred to as ferryl heme. There are two known intermediates: Compound I and Compound...
9.
Burton M, Cresser-Brown J, Thomas M, Portolano N, Basran J, Freeman S, et al.
J Biol Chem
. 2020 Jul;
295(38):13277-13286.
PMID: 32723862
The EAG () family of voltage-gated K channels are important regulators of neuronal and cardiac action potential firing (excitability) and have major roles in human diseases such as epilepsy, schizophrenia,...
10.
Ortmayer M, Fisher K, Basran J, Wolde-Michael E, Heyes D, Levy C, et al.
ACS Catal
. 2020 Jun;
10(4):2735-2746.
PMID: 32550044
Nature employs a limited number of genetically encoded axial ligands to control diverse heme enzyme activities. Deciphering the functional significance of these ligands requires a quantitative understanding of how their...