Jason Link
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Explore the profile of Jason Link including associated specialties, affiliations and a list of published articles.
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20
Citations
680
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Recent Articles
1.
Labora A, Shimizu T, Moore A, Premji A, Armstrong W, Chen K, et al.
Ann Surg Oncol
. 2024 Nov;
32(2):1197-1198.
PMID: 39557724
No abstract available.
2.
Labora A, Shimizu T, Moore A, Premji A, Armstrong W, Chen K, et al.
Ann Surg Oncol
. 2024 Jun;
31(10):6875-6882.
PMID: 38909116
Purpose: DOTATATE PET/CT (DOTATATE) is superior to conventional imaging in detecting metastasis for gastroenteropancreatic neuroendocrine tumors (GEP-NETs). However, limited availability, high-cost, and additive radiation exposure necessitate guidelines for its use....
3.
Shimizu T, Maeda S, Link J, Deranteriassian A, Premji A, Verma A, et al.
Surgery
. 2024 Feb;
175(5):1377-1385.
PMID: 38365548
Background: Neoadjuvant therapy is being increasingly used for patients with pancreatic cancer. The role of adjuvant therapy in these patients is unclear. The purpose of this study was to identify...
4.
Labora A, Lee H, Chan C, Tabornal E, Le T, Rashid K, et al.
STAR Protoc
. 2023 Mar;
4(2):102163.
PMID: 36930646
Here, we present a protocol to generate a murine model of liver metastasis by directly injecting tumor cells into the portal vein under ultrasound guidance. We describe steps for animal...
5.
Mulqueen R, Pokholok D, OConnell B, Thornton C, Zhang F, ORoak B, et al.
Nat Biotechnol
. 2021 Jul;
39(12):1574-1580.
PMID: 34226710
Single-cell combinatorial indexing (sci) with transposase-based library construction increases the throughput of single-cell genomics assays but produces sparse coverage in terms of usable reads per cell. We develop symmetrical strand...
6.
Liudahl S, Betts C, Sivagnanam S, Morales-Oyarvide V, da Silva A, Yuan C, et al.
Cancer Discov
. 2021 Mar;
11(8):2014-2031.
PMID: 33727309
Immunotherapies targeting aspects of T cell functionality are efficacious in many solid tumors, but pancreatic ductal adenocarcinoma (PDAC) remains refractory to these treatments. Deeper understanding of the PDAC immune ecosystem...
7.
Bhattacharyya S, Oon C, Kothari A, Horton W, Link J, Sears R, et al.
J Exp Med
. 2020 May;
217(8).
PMID: 32434218
Despite a critical role for MYC as an effector of oncogenic RAS, strategies to target MYC activity in RAS-driven cancers are lacking. In genetically engineered mouse models of lung and...
8.
Hundeyin M, Kurz E, Mishra A, Rossi J, Liudahl S, Leis K, et al.
Cancer Discov
. 2019 Jul;
9(9):1288-1305.
PMID: 31266770
Unconventional T-lymphocyte populations are emerging as important regulators of tumor immunity. Despite this, the role of TCRαβCD4CD8NK1.1 innate αβ T cells (iαβT) in pancreatic ductal adenocarcinoma (PDA) has not been...
9.
Auciello F, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, et al.
Cancer Discov
. 2019 Mar;
9(5):617-627.
PMID: 30837243
Pancreatic ductal adenocarcinoma (PDAC) develops a pronounced stromal response reflecting an aberrant wound-healing process. This stromal reaction features transdifferentiation of tissue-resident pancreatic stellate cells (PSC) into activated cancer-associated fibroblasts, a...
10.
Farrell A, Joly M, Allen-Petersen B, Worth P, Lanciault C, Sauer D, et al.
Nat Commun
. 2017 Nov;
8(1):1728.
PMID: 29170413
Intratumoral phenotypic heterogeneity has been described in many tumor types, where it can contribute to drug resistance and disease recurrence. We analyzed ductal and neuroendocrine markers in pancreatic ductal adenocarcinoma,...