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Jason J Paris

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Articles 74
Citations 1194
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Recent Articles
1.
Hahn Y, Nass S, Marks W, Paris J, Hauser K, Knapp P
Neurosci Lett . 2024 Nov; 845():138071. PMID: 39615581
Combined and highly active anti-retroviral therapies (cART) have transitioned HIV into a more chronic disease. Roughly half of people living with HIV (PLWH) still experience neurocognitive disorders, albeit less severely...
2.
Boullard N, Paris J, Shariat-Madar Z, Mahdi F
Molecules . 2024 May; 29(10). PMID: 38792081
Prolylcarboxypeptidase (PRCP, PCP, Lysosomal Pro-X-carboxypeptidase, Angiotensinase C) controls angiotensin- and kinin-induced cell signaling. Elevation of PRCP appears to be activated in chronic inflammatory diseases [cardiovascular disease (CVD), diabetes] in proportion...
3.
Hamadani C, Mahdi F, Merrell A, Flanders J, Cao R, Vashisth P, et al.
Adv Sci (Weinh) . 2024 Apr; 11(23):e2305484. PMID: 38572510
Delivering cargo to the central nervous system (CNS) remains a pharmacological challenge. For infectious diseases such as HIV, the CNS acts as a latent reservoir that is inadequately managed by...
4.
Paudel P, Pandey P, Paris J, Ashpole N, Mahdi F, Tian J, et al.
J Nat Prod . 2023 Jul; 86(7):1786-1792. PMID: 37450763
Bioassay-guided fractionation of the essential oil of led to the identification of α-santalol () and β-santalol () as new chemotypes of cannabinoid receptor type II (CB) ligands with values of...
5.
Moss E, Mahdi F, Worth C, Paris J
Viruses . 2023 Feb; 15(2). PMID: 36851638
Despite the benefits of combinatorial antiretroviral therapies (cART), virotoxic HIV proteins are still detectable within the central nervous system. Approximately half of all cART-treated patients contend with neurological impairments. The...
6.
Hamadani C, Mahdi F, Merrell A, Flanders J, Cao R, Vashisth P, et al.
Res Sq . 2023 Feb; PMID: 36824802
Delivering cargo to the central nervous system (CNS) remains a pharmacological challenge. For infectious diseases such as HIV, the CNS acts as a latent reservoir that is inadequately managed by...
7.
Akins N, Salahuddin M, Pandey P, Kim S, Mahdi F, Khan M, et al.
ACS Chem Neurosci . 2023 Feb; 14(5):958-976. PMID: 36795782
The kappa opioid receptor (KOR) is involved in the regulation of both the reward and mood processes. Recent reports find that the use of drugs of abuse increases the production...
8.
Khan M, Mahdi F, Penfornis P, Akins N, Hossain M, Kim S, et al.
Bioorg Med Chem . 2023 Jan; 78:117137. PMID: 36603398
In cancer cells, glutaminolysis is the primary source of biosynthetic precursors. Recent efforts to develop amino acid analogues to inhibit glutamine metabolism in cancer have been extensive. Our lab recently...
9.
Ahmed H, Ticar B, Black I, Mahdi F, Shami A, Misra S, et al.
Glycoconj J . 2022 Dec; 40(1):33-46. PMID: 36454453
Marcia hiantina (Mollusca, Bivalvia) (Lamarck, 1818), is an edible clam mainly distributed along the tropical coastal regions. Recent researches have demonstrated that clams can possess compounds, including polysaccharides, with a...
10.
Qrareya A, Wise N, Hodges E, Mahdi F, Stewart Jr J, Paris J
Viruses . 2022 Oct; 14(10). PMID: 36298745
Cardiovascular disorder (CVD) is a common comorbidity in people living with HIV (PLWH). Although the underlying mechanisms are unknown, virotoxic HIV proteins, such as the trans-activator of transcription (Tat), likely...