Pamela E Knapp
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Explore the profile of Pamela E Knapp including associated specialties, affiliations and a list of published articles.
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93
Citations
2983
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Recent Articles
1.
Simons C, Kim S, Hahn Y, Boake-Agyei A, Nass S, Vo P, et al.
ASN Neuro
. 2025 Jan;
17(1):2447338.
PMID: 39805095
People living with HIV (PLWH) experience HIV-associated neurocognitive disorders (HAND), even though combination antiretroviral therapy (cART) suppresses HIV replication. HIV-1 transactivator of transcription (HIV-1 Tat) contributes to the development of...
2.
Hahn Y, Nass S, Marks W, Paris J, Hauser K, Knapp P
Neurosci Lett
. 2024 Nov;
845():138071.
PMID: 39615581
Combined and highly active anti-retroviral therapies (cART) have transitioned HIV into a more chronic disease. Roughly half of people living with HIV (PLWH) still experience neurocognitive disorders, albeit less severely...
3.
Yarotskyy V, Contois L, Hahn Y, Nass S, Knapp P, Hauser K
Neurosci Lett
. 2024 Nov;
844():138032.
PMID: 39491780
Intracellular chloride (Cl) homeostasis is a critical regulator of neuronal excitability. Voltage-dependent neuronal Cl channels remain the least understood in terms of their role as a source of Cl entry...
4.
5.
Yarotskyy V, Nass S, Hahn Y, Contois L, Rory McQuiston A, Knapp P, et al.
J Neurophysiol
. 2024 Aug;
132(3):1056-1073.
PMID: 39110896
Besides having high potency and efficacy at the µ-opioid (MOR) and other opioid receptor types, fentanyl has some affinity for some adrenergic receptor types, which may underlie its unique pathophysiological...
6.
Lark A, Nass S, Hahn Y, Gao B, Milne G, Knapp P, et al.
J Neurochem
. 2024 Feb;
168(3):185-204.
PMID: 38308495
Despite the advent of combination anti-retroviral therapy (cART), nearly half of people infected with HIV treated with cART still exhibit HIV-associated neurocognitive disorders (HAND). HAND can be worsened by co-morbid...
7.
Nass S, Hahn Y, Ohene-Nyako M, McLane V, Damaj M, Thacker 2nd L, et al.
Viruses
. 2023 Mar;
15(3.
PMID: 36992299
Opioid use disorder (OUD) and HIV are comorbid epidemics that can increase depression. HIV and the viral protein Tat can directly induce neuronal injury within reward and emotionality brain circuitry,...
8.
Ohene-Nyako M, Nass S, Richard H, Lukande R, Nicol M, McRae M, et al.
ASN Neuro
. 2023 Mar;
15:17590914231158218.
PMID: 36890725
HIV/HIV-1 Tat and morphine independently increase pathologic phosphorylation of TAR DNA binding protein 43 in the striatum. HIV- and opioid-induced pathologic phosphorylation of TAR DNA binding protein 43 may involve...
9.
Flounlacker K, Hahn Y, Xu R, Simons C, Tian T, Hauser K, et al.
J Neurovirol
. 2023 Feb;
29(1):15-26.
PMID: 36853588
HIV-associated neurocognitive disorders (HAND) remain pervasive even with increased efficacy/use of antiretroviral therapies. Opioid use/abuse among HIV + individuals is documented to exacerbate CNS deficits. White matter (WM) alterations, including...
10.
Hauser K, Ohene-Nyako M, Knapp P
Curr Opin Neurobiol
. 2022 Dec;
78:102653.
PMID: 36584655
Opioid use disorder (OUD) has become a national crisis and contributes to the spread of human immunodeficiency virus (HIV) infection. Emerging evidence and advances in experimental models, methodology, and our...