Jason A Heth
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Explore the profile of Jason A Heth including associated specialties, affiliations and a list of published articles.
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34
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1582
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Recent Articles
1.
Serhan H, Bao L, Cheng X, Qin Z, Liu C, Heth J, et al.
NPJ Breast Cancer
. 2024 Jun;
10(1):43.
PMID: 38858374
Fatty acid synthesis (FAS) has been shown to play a key role in the survival of brain-metastatic (BM) breast cancer. We demonstrate that the fatty acid synthase inhibitor TVB-2640 synergizes...
2.
Al-Holou W, Wang H, Ravikumar V, Shankar S, Oneka M, Fehmi Z, et al.
Neoplasia
. 2023 Jan;
36:100872.
PMID: 36621024
Purpose: Glioblastoma(GBM) is a lethal disease characterized by inevitable recurrence. Here we investigate the molecular pathways mediating resistance, with the goal of identifying novel therapeutic opportunities. Experimental Design: We developed...
3.
Liau L, Ashkan K, Brem S, Campian J, Trusheim J, Iwamoto F, et al.
JAMA Oncol
. 2022 Nov;
9(1):112-121.
PMID: 36394838
Importance: Glioblastoma is the most lethal primary brain cancer. Clinical outcomes for glioblastoma remain poor, and new treatments are needed. Objective: To investigate whether adding autologous tumor lysate-loaded dendritic cell...
4.
Jiang C, Bhattacharya A, Linzey J, Joshi R, Cha S, Srinivasan S, et al.
Neurosurgery
. 2022 Mar;
90(6):758-767.
PMID: 35343469
Background: Accurate specimen analysis of skull base tumors is essential for providing personalized surgical treatment strategies. Intraoperative specimen interpretation can be challenging because of the wide range of skull base...
5.
Picton P, Vlisides P, Teig M, Heth J, Orringer D, Brooks J, et al.
J Clin Monit Comput
. 2022 Feb;
36(4):1227-1232.
PMID: 35113286
Controversy surrounds regional cerebral oximetry (rSO) because extracranial contamination and unmeasured changes in cerebral arterial:venous ratio confound readings. Correlation of rSO with brain tissue oxygen (PbrO), a "gold standard" for...
6.
Kozlowski J, VanKoevering K, Heth J
J Clin Neurosci
. 2021 Jul;
90:238-243.
PMID: 34275556
Laser interstitial thermal therapy (LITT) is a minimally invasive neurosurgical technique that has been demonstrated to successfully ablate intracranial tumors. While LITT for supratentorial lesions can often be straightforward, ablation...
7.
8.
Hollon T, Pandian B, Urias E, Save A, Adapa A, Srinivasan S, et al.
Neuro Oncol
. 2020 Jul;
23(1):144-155.
PMID: 32672793
Background: Detection of glioma recurrence remains a challenge in modern neuro-oncology. Noninvasive radiographic imaging is unable to definitively differentiate true recurrence versus pseudoprogression. Even in biopsied tissue, it can be...
9.
Hollon T, Pandian B, Adapa A, Urias E, Save A, Khalsa S, et al.
Nat Med
. 2020 Jan;
26(1):52-58.
PMID: 31907460
Intraoperative diagnosis is essential for providing safe and effective care during cancer surgery. The existing workflow for intraoperative diagnosis based on hematoxylin and eosin staining of processed tissue is time,...
10.
Nadel J, Wilkinson D, Linzey J, Maher C, Kotagal V, Heth J
Neurosurgery
. 2019 Aug;
86(6):843-850.
PMID: 31420654
Background: Research on age-related complications secondary to shunts in normal pressure hydrocephalus (NPH) is primarily limited to single-center studies and small cohorts. Objective: To determine the rates of hospital readmission...