Daniel A Orringer
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Explore the profile of Daniel A Orringer including associated specialties, affiliations and a list of published articles.
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67
Citations
1653
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Recent Articles
1.
Murphy Z, Bianchini E, Smith A, Korner L, Russell T, Reinecke D, et al.
Med
. 2025 Feb;
:100604.
PMID: 40010345
Background: The diagnosis and treatment of tumors often depend on molecular-genetic data. However, rapid and iterative access to molecular data is not currently feasible during surgery, complicating intraoperative diagnosis and...
2.
Alber D, Yang Z, Alyakin A, Yang E, Rai S, Valliani A, et al.
Nat Med
. 2025 Jan;
31(2):618-626.
PMID: 39779928
The adoption of large language models (LLMs) in healthcare demands a careful analysis of their potential to spread false medical knowledge. Because LLMs ingest massive volumes of data from the...
3.
Mandelberg N, Hodges T, Wang T, McGranahan T, Olson J, Orringer D
J Neurooncol
. 2025 Jan;
172(1):195-218.
PMID: 39747718
Question: What are the optimal neuropathological techniques to diagnose low-grade diffuse glioma in the adult? Recommendation: Level I Histopathological analysis of a representative surgical sample of the lesion should be...
4.
Mannas M, Deng F, Ion-Margineanu A, Freudiger C, Lough L, Huang W, et al.
J Urol
. 2024 Dec;
101097JU0000000000004393.
PMID: 39689226
Purpose: Balancing surgical margins and functional outcomes is crucial during radical prostatectomy for prostate cancer. Stimulated Raman histology (SRH) is a novel, real-time imaging technique that provides histologic images of...
5.
Reinecke D, Maarouf N, Smith A, Alber D, Markert J, Goff N, et al.
Neuro Oncol
. 2024 Dec;
PMID: 39673805
Background: Accurate intraoperative diagnosis is crucial for differentiating between primary CNS lymphoma (PCNSL) and other CNS entities, guiding surgical decision-making, but represents significant challenges due to overlapping histomorphological features, time...
6.
Kondepudi A, Pekmezci M, Hou X, Scotford K, Jiang C, Rao A, et al.
Nature
. 2024 Nov;
637(8045):439-445.
PMID: 39537921
A critical challenge in glioma treatment is detecting tumour infiltration during surgery to achieve safe maximal resection. Unfortunately, safely resectable residual tumour is found in the majority of patients with...
7.
Reinecke D, Maroouf N, Smith A, Alber D, Markert J, Goff N, et al.
medRxiv
. 2024 Sep;
PMID: 39252932
Accurate intraoperative diagnosis is crucial for differentiating between primary CNS lymphoma (PCNSL) and other CNS entities, guiding surgical decision-making, but represents significant challenges due to overlapping histomorphological features, time constraints,...
8.
Mannas M, Deng F, Ion-Margineanu A, Freudiger C, Jones D, Hoskoppal D, et al.
Urol Oncol
. 2024 Aug;
43(1):64.e19-64.e25.
PMID: 39129081
Background: In-field or in-margin recurrence after partial gland cryosurgical ablation (PGCA) of prostate cancer (PCa) remains a limitation of the paradigm. Stimulated Raman histology (SRH) is a novel microscopic technique...
9.
Nasir-Moin M, Wadiura L, Sacalean V, Juros D, Movahed-Ezazi M, Lock E, et al.
Nat Biomed Eng
. 2024 Jul;
8(6):672-688.
PMID: 38987630
The most widely used fluorophore in glioma-resection surgery, 5-aminolevulinic acid (5-ALA), is thought to cause the selective accumulation of fluorescent protoporphyrin IX (PpIX) in tumour cells. Here we show that...
10.
Murphy Z, Bianchini E, Smith A, Korner L, Russell T, Reinecke D, et al.
medRxiv
. 2024 Jun;
PMID: 38854127
The diagnosis and treatment of tumors often depends on molecular-genetic data. However, rapid and iterative access to molecular data is not currently feasible during surgery, complicating intraoperative diagnosis and precluding...