Jasmeet S Reyat
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Explore the profile of Jasmeet S Reyat including associated specialties, affiliations and a list of published articles.
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20
Citations
386
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Recent Articles
1.
Reyat J, Sommerfeld L, OReilly M, Cardoso V, Thiemann E, Khan A, et al.
Cardiovasc Res
. 2024 Aug;
120(15):1907-1923.
PMID: 39129206
Aims: Reduced left atrial PITX2 is associated with atrial cardiomyopathy and atrial fibrillation (AF). PITX2 is restricted to left atrial cardiomyocytes (aCMs) in the adult heart. The links between PITX2...
2.
Olijnik A, Rodriguez-Romera A, Wong Z, Shen Y, Reyat J, Jooss N, et al.
Nat Protoc
. 2024 Mar;
19(7):2117-2146.
PMID: 38532070
The bone marrow supports and regulates hematopoiesis, responding to physiological requirements for blood cell production over ontogeny and during pathological challenges. Interactions between hematopoietic cells and niche components are challenging...
3.
Chua W, Cardoso V, Guasch E, Sinner M, Al-Taie C, Brady P, et al.
Sci Rep
. 2023 Oct;
13(1):16743.
PMID: 37798357
Early detection of atrial fibrillation (AF) enables initiation of anticoagulation and early rhythm control therapy to reduce stroke, cardiovascular death, and heart failure. In a cross-sectional, observational study, we aimed...
4.
Reyat J, di Maio A, Grygielska B, Pike J, Kemble S, Rodriguez-Romero A, et al.
Front Cardiovasc Med
. 2023 Sep;
10:1156759.
PMID: 37727305
Introduction: Recent advances in human cardiac 3D approaches have yielded progressively more complex and physiologically relevant culture systems. However, their application in the study of complex pathological processes, such as...
5.
Hall C, Law J, Reyat J, Cumberland M, Hang S, Vo N, et al.
Sci Rep
. 2023 Jul;
13(1):12137.
PMID: 37495732
Activation of cardiac fibroblasts and differentiation to myofibroblasts underlies development of pathological cardiac fibrosis, leading to arrhythmias and heart failure. Myofibroblasts are characterised by increased α-smooth muscle actin (α-SMA) fibre...
6.
Broadway-Stringer S, Jiang H, Wadmore K, Hooper C, Douglas G, Steeples V, et al.
Cells
. 2023 Mar;
12(5).
PMID: 36899856
Pathogenic variants in , coding for alpha-actinin 2, are known to be rare causes of Hypertrophic Cardiomyopathy. However, little is known about the underlying disease mechanisms. Adult heterozygous mice carrying...
7.
Khan A, Rodriguez-Romera A, Reyat J, Olijnik A, Colombo M, Wang G, et al.
Cancer Discov
. 2022 Nov;
13(2):364-385.
PMID: 36351055
Significance: We present a human bone marrow organoid that supports the growth of primary cells from patients with myeloid and lymphoid blood cancers. This model allows for mechanistic studies of...
8.
Colicchia M, Schrottmaier W, Perrella G, Reyat J, Begum J, Slater A, et al.
Blood
. 2022 Aug;
140(24):2626-2643.
PMID: 36026606
S100A8/A9, also known as "calprotectin" or "MRP8/14," is an alarmin primarily secreted by activated myeloid cells with antimicrobial, proinflammatory, and prothrombotic properties. Increased plasma levels of S100A8/A9 in thrombo-inflammatory diseases...
9.
Khan A, Reyat J, Hill H, Bourne J, Colicchia M, Newby M, et al.
Cardiovasc Res
. 2022 Jun;
118(15):3085-3096.
PMID: 35709328
Aims: Thrombotic complications and vasculopathy have been extensively associated with severe COVID-19 infection; however, the mechanisms inducing endotheliitis and the disruption of endothelial integrity in the microcirculation are poorly understood....
10.
O Brien S, Holmes A, Johnson D, Kabir S, O Shea C, O Reilly M, et al.
J Mol Cell Cardiol
. 2022 Feb;
166:23-35.
PMID: 35114252
Atrial fibrillation (AF) affects over 1% of the population and is a leading cause of stroke and heart failure in the elderly. A feared side effect of sodium channel blocker...