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Jared Nordman

Explore the profile of Jared Nordman including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 1033
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Recent Articles
1.
Das S, Caballero M, Kolesnikova T, Zhimulev I, Koren A, Nordman J
Genetics . 2021 Nov; 219(3). PMID: 34740250
Regulation of DNA replication and copy number is necessary to promote genome stability and maintain cell and tissue function. DNA replication is regulated temporally in a process known as replication...
2.
Nordman J, Orr-Weaver T
Development . 2012 Jan; 139(3):455-64. PMID: 22223677
As development unfolds, DNA replication is not only coordinated with cell proliferation, but is regulated uniquely in specific cell types and organs. This differential regulation of DNA synthesis requires crosstalk...
3.
Sher N, Bell G, Li S, Nordman J, Eng T, Eaton M, et al.
Genome Res . 2011 Nov; 22(1):64-75. PMID: 22090375
Precise DNA replication is crucial for genome maintenance, yet this process has been inherently difficult to study on a genome-wide level in untransformed differentiated metazoan cells. To determine how metazoan...
4.
Nordman J, Wright A
J Bacteriol . 2011 Jul; 193(17):4531-3. PMID: 21725024
Escherichia coli nucleoside diphosphate (NDP) kinase mutants have an increased frequency of spontaneous mutation, possibly due to uracil misincorporation into DNA. Here we show that NDP kinase mutants are dependent...
5.
Kim J, Nordman J, Xie F, Kashevsky H, Eng T, Li S, et al.
Genes Dev . 2011 Jul; 25(13):1384-98. PMID: 21724831
In metazoans, how replication origins are specified and subsequently activated is not well understood. Drosophila amplicons in follicle cells (DAFCs) are genomic regions that undergo rereplication to increase DNA copy...
6.
Roy S, Ernst J, Kharchenko P, Kheradpour P, Negre N, Eaton M, et al.
Science . 2010 Dec; 330(6012):1787-97. PMID: 21177974
To gain insight into how genomic information is translated into cellular and developmental programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) project is comprehensively mapping transcripts, histone modifications,...
7.
Nordman J, Li S, Eng T, MacAlpine D, Orr-Weaver T
Genome Res . 2010 Dec; 21(2):175-81. PMID: 21177957
Polyploid or polytene cells, which have more than 2C DNA content, are widespread throughout nature and present in most differentiated Drosophila tissues. These cells also can display differential replication, that...
8.
Nordman J, Wright A
Proc Natl Acad Sci U S A . 2008 Jul; 105(29):10197-202. PMID: 18621712
Loss of nucleoside diphosphate kinase (Ndk) function in Escherichia coli results in an increased frequency of spontaneous mutation and an imbalance in dNTP pool levels. It is presumed that the...
9.
Nordman J, Skovgaard O, Wright A
Mol Microbiol . 2007 Mar; 64(1):125-38. PMID: 17376077
Over-initiation of DNA replication in cells containing the cold-sensitive dnaA(cos) allele has been shown to lead to extensive DNA damage, potentially due to head-to-tail replication fork collisions that ultimately lead...