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Janine Mok

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Articles 6
Citations 307
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Recent Articles
1.
Schlecht U, Mok J, Dallett C, Berka J
Sci Rep . 2017 Jul; 7(1):5252. PMID: 28701704
Single molecule sequencing (SMS) platforms enable base sequences to be read directly from individual strands of DNA in real-time. Though capable of long read lengths, SMS platforms currently suffer from...
2.
Mok J, Mindrinos M, Davis R, Javanmard M
Proc Natl Acad Sci U S A . 2014 Jan; 111(6):2110-5. PMID: 24449893
Global studies of the human proteome have revealed a plethora of putative protein biomarkers. However, their application for early disease detection remains at a standstill without suitable methods to realize...
3.
Mok J, Zhu X, Snyder M
Expert Rev Proteomics . 2011 Nov; 8(6):775-86. PMID: 22087660
Protein phosphorylation continues to be regarded as one of the most important post-translational modifications found in eukaryotes and has been implicated in key roles in the development of a number...
4.
Lam H, Kim P, Mok J, Tonikian R, Sidhu S, Turk B, et al.
BMC Bioinformatics . 2010 May; 11:243. PMID: 20459839
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protein domains such as the SH3 binding...
5.
Mok J, Kim P, Lam H, Piccirillo S, Zhou X, Jeschke G, et al.
Sci Signal . 2010 Feb; 3(109):ra12. PMID: 20159853
Phosphorylation is a universal mechanism for regulating cell behavior in eukaryotes. Although protein kinases target short linear sequence motifs on their substrates, the rules for kinase substrate recognition are not...
6.
Mok J, Im H, Snyder M
Nat Protoc . 2009 Dec; 4(12):1820-7. PMID: 20010933
Herein, we describe a protocol for the global identification of in vitro substrates targeted by protein kinases using protein microarray technology. Large numbers of fusion proteins tagged at their carboxy-termini...