Janet A Brunton
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Explore the profile of Janet A Brunton including associated specialties, affiliations and a list of published articles.
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33
Citations
260
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Recent Articles
1.
Randunu R, Alawaini K, Huber L, Randell E, Brunton J, Bertolo R
J Nutr
. 2024 Sep;
154(11):3353-3364.
PMID: 39270853
Background: Early nutritional challenges can lead to permanent metabolic changes, increasing risk of developing chronic diseases later in life. Total parenteral nutrition (TPN) is a life-saving nutrition regimen, used especially...
2.
Asiriwardhana M, Dinesh O, Brunton J, Bertolo R
J Nutr
. 2024 Mar;
154(5):1571-1581.
PMID: 38527737
Background: Creatine plays a significant role in energy metabolism and positively impacts anaerobic energy capacity, muscle mass, and physical performance. Endogenous creatine synthesis requires guanidinoacetic acid (GAA) and methionine. GAA...
3.
Kirupananthan D, Bertolo R, Brunton J
J Nutr
. 2022 Apr;
152(8):1843-1850.
PMID: 35481706
Background: Parenteral nutrition (PN) is often a necessity for preterm infants; however, prolonged PN leads to gut atrophy, weakened gut barrier function, and a higher risk of intestinal infections. Peptide...
4.
Dinesh O, Kankayaliyan T, Rademacher M, Tomlinson C, Bertolo R, Brunton J
J Nutr
. 2021 Jan;
151(3):531-539.
PMID: 33437999
Background: Suckling piglets synthesize most of their creatine requirement, which consumes substantial amounts of arginine in order to synthesize guanidinoacetic acid (GAA) and methionine in order to transmethylate GAA to...
5.
Robinson J, McBreairty L, Ryan R, Randunu R, Walsh C, Martin G, et al.
PLoS One
. 2020 Jan;
15(1):e0226806.
PMID: 31905208
The emergence of creatine as a potential cognitive enhancement supplement for humans prompted an investigation as to whether supplemental creatine could enhance spatial memory in young swine. We assessed memory...
6.
Dinesh O, Brunton J, Bertolo R
J Nutr
. 2019 Nov;
150(3):443-449.
PMID: 31687740
Background: Arginine:glycine amidinotransferase, necessary for the conversion of arginine (Arg) to guanidinoacetic acid (GAA), is expressed mainly in kidney and pancreas. The methylation of GAA to creatine (Cre) primarily occurs...
7.
Huber L, Lee T, LeDrew R, Dodge M, Brunton J, Bertolo R
J Pediatr Gastroenterol Nutr
. 2019 Oct;
69(6):719-725.
PMID: 31568154
Objectives: The purpose of the present study was to determine if protecting parenteral nutrition solutions from ambient light and supplementing with N-acetylcysteine (NAC) improves mesenteric blood flow, gut morphology, and...
8.
Robinson J, McBreairty L, Randell E, Harding S, Bartlett R, Brunton J, et al.
J Nutr Biochem
. 2018 Jul;
59:129-135.
PMID: 29986307
Methionine partitioning between protein turnover and a considerable pool of transmethylation precursors is a critical process in the neonate. Transmethylation yields homocysteine, which is either oxidized to cysteine (i.e., transsulfuration),...
9.
Dinesh O, Bertolo R, Brunton J
Pediatr Res
. 2017 Aug;
83(1-1):135-141.
PMID: 28846669
BackgroundCreatine is not included in commercial pediatric parenteral products; the entire creatine requirement must be met by de novo synthesis from arginine during parenteral nutrition (PN). Poor arginine status is...
10.
Munasinghe L, Robinson J, Harding S, Brunton J, Bertolo R
J Nutr
. 2017 Jan;
147(2):202-210.
PMID: 28053172
Background: The neonatal gastrointestinal tract extracts the majority of dietary threonine on the first pass to maintain synthesis of threonine-rich mucins in mucus. As dietary threonine becomes limiting, this extraction...