Janet A Brunton
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Explore the profile of Janet A Brunton including associated specialties, affiliations and a list of published articles.
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33
Citations
260
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Recent Articles
11.
Robinson J, Harding S, Brunton J, Bertolo R
J Nutr
. 2016 Sep;
146(10):2007-2012.
PMID: 27581577
Background: The neonatal methionine requirement must consider not only the high demand for rapid tissue protein expansion but also the demands as the precursor for a suite of critical transmethylation...
12.
Robinson J, Bartlett R, Harding S, Randell E, Brunton J, Bertolo R
Amino Acids
. 2016 Aug;
48(12):2821-2830.
PMID: 27562792
Methionine metabolism is critical during development with significant requirements for protein synthesis and transmethylation reactions. However, separate requirements of methionine for protein synthesis and transmethylation are difficult to define because...
13.
Robinson J, McBreairty L, Randell E, Brunton J, Bertolo R
J Nutr Biochem
. 2016 Jul;
35:81-86.
PMID: 27469995
Methionine is required for protein synthesis and provides a methyl group for >50 critical transmethylation reactions including creatine and phosphatidylcholine synthesis as well as DNA and protein methylation. However, the...
14.
Nosworthy M, Brunton J
Pediatr Res
. 2016 Apr;
80(2):293-8.
PMID: 27055186
Background: PepT1 transports dietary and bacterial peptides in the gut. We hypothesized that cysteinyl-glycine would ameliorate the inflammatory effect of a bacterial peptide, formyl-methionyl-leucyl-phenylalanine (fMLP), in both sow-fed and parenterally-fed...
15.
McBreairty L, Robinson J, Harding S, Randell E, Brunton J, Bertolo R
Eur J Nutr
. 2015 Oct;
55(8):2423-2430.
PMID: 26419586
Purpose: Both folate and betaine (synthesized from choline) are nutrients used to methylate homocysteine to reform the amino acid methionine following donation of its methyl group; however, it is unclear...
16.
McBreairty L, Robinson J, Furlong K, Brunton J, Bertolo R
PLoS One
. 2015 Jun;
10(6):e0131563.
PMID: 26110793
Creatine (Cr) is an important high-energy phosphate buffer in tissues with a high energy demand such as muscle and brain and is consequently a highly consumed nutritional supplement. Creatine is...
17.
Nosworthy M, Dodge M, Bertolo R, Brunton J
Clin Nutr
. 2015 Jun;
35(4):852-8.
PMID: 26073670
Unlabelled: PepT1, a di/tripeptide transporter, is preferentially preserved over free amino acid transporters in situations of gut stress. Therefore, our objective was to determine the impact of enterally delivered dipeptide-containing...
18.
Dinesh O, Dodge M, Baldwin M, Bertolo R, Brunton J
JPEN J Parenter Enteral Nutr
. 2013 Aug;
38(8):973-81.
PMID: 23980133
Background: Arginine is an indispensable amino acid in neonates; de novo synthesis of arginine occurs in the small intestine (SI) but is reduced during parenteral nutrition (PN), limiting the arginine...
19.
McBreairty L, McGowan R, Brunton J, Bertolo R
J Nutr
. 2013 Apr;
143(6):804-9.
PMID: 23616507
Methionine is the main source of methyl groups that are partitioned to synthesize various methylated products including creatine, phosphatidylcholine (PC), and methylated DNA. Whether increased methylation of 1 product can...
20.
Nosworthy M, Bertolo R, Brunton J
Br J Nutr
. 2012 Dec;
110(2):275-81.
PMID: 23234698
The H⁺-coupled transporter, peptide transporter 1 (PepT1), is responsible for the uptake of dietary di- and tripeptides in the intestine. Using an in vivo continuously perfused gut loop model in...