Jane B Florer
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Explore the profile of Jane B Florer including associated specialties, affiliations and a list of published articles.
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7
Citations
510
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Recent Articles
1.
Sun M, Chen S, Adams S, Florer J, Liu H, Kao W, et al.
J Cell Sci
. 2011 Dec;
124(Pt 23):4096-105.
PMID: 22159420
Collagen V is a regulatory fibril-forming collagen that forms heterotypic fibrils with collagen I. Deletion of collagen V in the mouse is associated with a lack of fibril assembly in...
2.
Wenstrup R, Smith S, Florer J, Zhang G, Beason D, Seegmiller R, et al.
J Biol Chem
. 2011 Apr;
286(23):20455-65.
PMID: 21467034
Collagens V and XI comprise a single regulatory type of fibril-forming collagen with multiple isoforms. Both co-assemble with collagen I or II to form heterotypic fibrils and have been implicated...
3.
Lincoln J, Florer J, Deutsch G, Wenstrup R, Yutzey K
Dev Dyn
. 2006 Oct;
235(12):3295-305.
PMID: 17029294
Genetic mutations in minor fibrillar collagen types Va1 (ColVa1) and XIa1 (ColXI) have been identified in connective tissue disorders including Ehlers-Danlos syndrome and chondrodysplasias. ColVa1+/- and ColXIa1-/- mutant mice recapitulate...
4.
Wenstrup R, Florer J, Davidson J, Phillips C, Pfeiffer B, Menezes D, et al.
J Biol Chem
. 2006 Feb;
281(18):12888-95.
PMID: 16492673
The most commonly identified mutations causing Ehlers-Danlos syndrome (EDS) classic type result in haploinsufficiency of proalpha1(V) chains of type V collagen, a quantitatively minor collagen that co-assembles with type I...
5.
Peace B, Florer J, Witte D, Smicun Y, Toudjarska I, Wu G, et al.
Mol Ther
. 2005 Jun;
12(1):128-36.
PMID: 15963928
Hammerhead ribozymes are small catalytic RNA molecules that can be targeted to any RNA molecule containing a putative cleavage site. We developed a vector (pCOLZ) that uses the COL1A1 promoter...
6.
Wenstrup R, Florer J, Brunskill E, Bell S, Chervoneva I, Birk D
J Biol Chem
. 2004 Sep;
279(51):53331-7.
PMID: 15383546
Vertebrate collagen fibrils are heterotypically composed of a quantitatively major and minor fibril collagen. In non-cartilaginous tissues, type I collagen accounts for the majority of the collagen mass, and collagen...
7.
Wenstrup R, Florer J, Cole W, Willing M, Birk D
J Cell Biochem
. 2004 Apr;
92(1):113-24.
PMID: 15095409
To examine mechanisms by which reduced type V collagen causes weakened connective tissues in the Ehlers-Danlos syndrome (EDS), we examined matrix deposition and collagen fibril morphology in long-term dermal fibroblast...