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Joy Lincoln

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Articles 71
Citations 2810
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Recent Articles
1.
Bluemn T, Kessler J, Kim A, Drnevich J, Lincoln J
Arterioscler Thromb Vasc Biol . 2025 Mar; PMID: 40079140
Background: Heart valve function requires a highly organized ECM (extracellular matrix) network that provides the necessary biomechanical properties needed to withstand pressure changes during each cardiac cycle. Lay down of...
2.
Lincoln J
Nat Cardiovasc Res . 2024 Aug; 3(8):888-889. PMID: 39196034
No abstract available.
3.
Gramling D, van Veldhuisen A, Damen F, Thatcher K, Liu F, McComb D, et al.
Ann Biomed Eng . 2024 Jun; 52(9):2596-2609. PMID: 38874705
Aortic valve (AV) disease is a common valvular lesion in the United States, present in about 5% of the population at age 65 with increasing prevalence with advancing age. While...
4.
Thatcher K, Mattern C, Chaparro D, Goveas V, McDermott M, Fulton J, et al.
J Cardiovasc Dev Dis . 2023 Aug; 10(8). PMID: 37623368
Organization of extracellular matrix (ECM) components, including collagens, proteoglycans, and elastin, is essential for maintaining the structure and function of heart valves throughout life. Mutations in ECM genes cause connective...
5.
Kessler J, Bluemn T, DeCero S, Dutta P, Thatcher K, Mahnke D, et al.
J Mol Cell Cardiol . 2023 Aug; 183:1-13. PMID: 37579636
Cardiovascular calcification can occur in vascular and valvular structures and is commonly associated with calcium deposition and tissue mineralization leading to stiffness and dysfunction. Patients with chronic kidney disease and...
6.
McCallinhart P, Lee Y, Lee A, Anghelescu M, Tonniges J, Calomeni E, et al.
Front Physiol . 2023 Apr; 14:1154454. PMID: 37035668
Vascular stiffness is a predictor of cardiovascular disease and pulse wave velocity (PWV) is the current standard for measuring vascular stiffness. Mean arterial pressure is the largest confounding variable to...
7.
Maroney S, Siebert A, Martinez N, Rasmussen M, Peterson J, Weiler H, et al.
J Thromb Haemost . 2023 Jan; 21(3):639-651. PMID: 36696221
Background: Tissue factor pathway inhibitor (TFPI) is the primary inhibitor of events initiating the blood coagulation pathway. Tfpi mice die during embryonic development. The absence of protease-activated receptor (PAR) 4,...
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9.
Wang B, Wang X, Kenneth A, Drena A, Pacheco A, Kalvin L, et al.
Biofabrication . 2023 Jan; 15(2). PMID: 36626826
While current clinical utilization of large vascular grafts for vascular transplantation is encouraging, tissue engineering of small grafts still faces numerous challenges. This study aims to investigate the feasibility of...
10.
Yan S, Peng Y, Lu J, Shakil S, Shi Y, Crossman D, et al.
J Cell Sci . 2022 Aug; 135(17). PMID: 35946425
Mitral and tricuspid valves are essential for unidirectional blood flow in the heart. They are derived from similar cell sources, and yet congenital dysplasia affecting both valves is clinically rare,...