Jan T Liphardt
Overview
Explore the profile of Jan T Liphardt including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
929
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fast and parallel nanoscale three-dimensional tracking of heterogeneous mammalian chromatin dynamics
Gustavsson A, Ghosh R, Petrov P, Liphardt J, Moerner W
Mol Biol Cell
. 2022 Mar;
33(6):ar47.
PMID: 35352962
Chromatin organization and dynamics are critical for gene regulation. In this work we present a methodology for fast and parallel three-dimensional (3D) tracking of multiple chromosomal loci of choice over...
2.
Ruijgrok P, Ghosh R, Zemsky S, Nakamura M, Gong R, Ning L, et al.
Nat Chem Biol
. 2021 Feb;
17(5):540-548.
PMID: 33603247
Precision tools for spatiotemporal control of cytoskeletal motor function are needed to dissect fundamental biological processes ranging from intracellular transport to cell migration and division. Direct optical control of motor...
3.
Yang L, Ghosh R, Franklin J, Chen S, You C, Narayan R, et al.
PLoS Comput Biol
. 2020 Sep;
16(9):e1008193.
PMID: 32925919
Segmenting cell nuclei within microscopy images is a ubiquitous task in biological research and clinical applications. Unfortunately, segmenting low-contrast overlapping objects that may be tightly packed is a major bottleneck...
4.
Franklin J, Ghosh R, Shi Q, Reddick M, Liphardt J
Nat Commun
. 2020 Sep;
11(1):4581.
PMID: 32917893
Yes-associated protein 1 (YAP) is a transcriptional regulator with critical roles in mechanotransduction, organ size control, and regeneration. Here, using advanced tools for real-time visualization of native YAP and target...
5.
Northey J, Barrett A, Acerbi I, Hayward M, Talamantes S, Dean I, et al.
J Clin Invest
. 2020 Jul;
130(11):5721-5737.
PMID: 32721948
Women with dense breasts have an increased lifetime risk of malignancy that has been attributed to a higher epithelial density. Quantitative proteomics, collagen analysis, and mechanical measurements in normal tissue...
6.
Ghosh R, Shi Q, Yang L, Reddick M, Nikitina T, Zhurkin V, et al.
Nat Commun
. 2019 Jul;
10(1):3221.
PMID: 31324780
The Satb1 genome organizer regulates multiple cellular and developmental processes. It is not yet clear how Satb1 selects different sets of targets throughout the genome. Here we have used live-cell...
7.
Ban E, Wang H, Franklin J, Liphardt J, Janmey P, Shenoy V
Proc Natl Acad Sci U S A
. 2019 Mar;
116(14):6790-6799.
PMID: 30894480
While cells within tissues generate and sense 3D states of strain, the current understanding of the mechanics of fibrous extracellular matrices (ECMs) stems mainly from uniaxial, biaxial, and shear tests....
8.
Ghosh R, Franklin J, Draper W, Shi Q, Beltran B, Spakowitz A, et al.
Nat Chem Biol
. 2019 Mar;
15(4):401-409.
PMID: 30858596
We describe three optical tags, ArrayG, ArrayD and ArrayG/N, for intracellular tracking of single molecules over milliseconds to hours. ArrayG is a fluorogenic tag composed of a green fluorescent protein-nanobody...
9.
Ban E, Franklin J, Nam S, Smith L, Wang H, Wells R, et al.
Biophys J
. 2018 Feb;
114(2):450-461.
PMID: 29401442
Contractile cells can reorganize fibrous extracellular matrices and form dense tracts of fibers between neighboring cells. These tracts guide the development of tubular tissue structures and provide paths for the...
10.
Chen X, Shen Y, Draper W, Buenrostro J, Litzenburger U, Cho S, et al.
Nat Methods
. 2016 Nov;
13(12):1013-1020.
PMID: 27749837
Spatial organization of the genome plays a central role in gene expression, DNA replication, and repair. But current epigenomic approaches largely map DNA regulatory elements outside of the native context...