Jan Dorrie
Overview
Explore the profile of Jan Dorrie including associated specialties, affiliations and a list of published articles.
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80
Citations
1201
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Recent Articles
1.
Sauerer T, Bremm F, Beenen A, Heger L, Dudziak D, Bosch N, et al.
MedComm (2020)
. 2025 Feb;
6(3):e70111.
PMID: 39974665
No abstract available.
2.
Pfister F, Carnell L, Loffler L, Boosz P, Schaft N, Dorrie J, et al.
MedComm (2020)
. 2025 Jan;
6(1):e70039.
PMID: 39764559
Therapies against hematological malignancies using chimeric antigen receptors (CAR)-T cells have shown great potential; however, therapeutic success in solid tumors has been constrained due to limited tumor trafficking and infiltration,...
3.
Schaft N, Dorrie J
Methods Mol Biol
. 2024 Dec;
2883:79-107.
PMID: 39702705
RNA is a substance with various biological functions. It serves as blueprint for proteins and shuttles information from the genes to the protein factories of the cells. However, these factories-the...
4.
Myrda J, Bremm F, Schaft N, Dorrie J
Genes (Basel)
. 2024 Sep;
15(9).
PMID: 39336718
The large T antigen (LT) of the Merkel cell polyomavirus (MCPyV) is crucial for Merkel cell carcinoma (MCC), a rare but very aggressive form of neuroendocrine skin cancer. The clonal...
5.
Binder A, Bremm F, Dorrie J, Schaft N
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000381
The RNA world is wide, and besides mRNA, there is a variety of other RNA types, such as non-coding (nc)RNAs, which harbor various intracellular regulatory functions. This review focuses on...
6.
Roehnisch T, Martos-Contreras M, Manoochehri M, Nogueira M, Bremm F, Dorrie J, et al.
Front Immunol
. 2024 Jun;
15:1414737.
PMID: 38938562
This report details a case of pancreatic cancer with liver metastasis that exhibited a positive immune response to personalized immunization therapy. Our study involved the identification of neoantigens and their...
7.
Sauerer T, Albrecht L, Sievers N, Gerer K, Hoyer S, Dorrie J, et al.
Methods Mol Biol
. 2024 May;
2786:219-235.
PMID: 38814397
Electroporation (EP) of mRNA into human cells is a broadly applicable method to transiently express proteins of choice in a variety of different cell types. We have spent more than...
8.
Emilius L, Bremm F, Binder A, Schaft N, Dorrie J
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38731892
With the advent of immunotherapeutics, a new era in the combat against cancer has begun. Particularly promising are neo-epitope-targeted therapies as the expression of neo-antigens is tumor-specific. In turn, this...
9.
Lischer C, Eberhardt M, Flamann C, Berges J, Guse E, Wessely A, et al.
J Immunother Cancer
. 2024 May;
12(5).
PMID: 38724462
Background: Tumor-associated antigens and their derived peptides constitute an opportunity to design off-the-shelf mainline or adjuvant anti-cancer immunotherapies for a broad array of patients. A performant and rational antigen selection...
10.
Schaft N, Dorrie J, Schuler G, Schuler-Thurner B, Sallam H, Klein S, et al.
Front Immunol
. 2023 Sep;
14:1248867.
PMID: 37736099
The treatment of cancer was revolutionized within the last two decades by utilizing the mechanism of the immune system against malignant tissue in so-called cancer immunotherapy. Two main developments boosted...