Jan Dorrie
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Explore the profile of Jan Dorrie including associated specialties, affiliations and a list of published articles.
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80
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1201
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Recent Articles
11.
Pfister F, Dorrie J, Schaft N, Buchele V, Unterweger H, Carnell L, et al.
Front Immunol
. 2023 Sep;
14:1223695.
PMID: 37662937
Background: Immunotherapy of cancer is an emerging field with the potential to improve long-term survival. Thus far, adoptive transfer of tumor-specific T cells represents an effective treatment option for tumors...
12.
Heger L, Hatscher L, Liang C, Lehmann C, Amon L, Luhr J, et al.
Proc Natl Acad Sci U S A
. 2023 Aug;
120(33):e2300343120.
PMID: 37566635
Dendritic cells (DCs) are major regulators of innate and adaptive immune responses. DCs can be classified into plasmacytoid DCs and conventional DCs (cDCs) type 1 and 2. Murine and human...
13.
Harrer D, Dorrie J, Schaft N
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768665
The development of chimeric antigen receptor T cells (CAR-T cells) has marked a new era in cancer immunotherapy. Based on a multitude of durable complete remissions in patients with hematological...
14.
Lutz M, Ali S, Audiger C, Autenrieth S, Berod L, Bigley V, et al.
Eur J Immunol
. 2022 Oct;
53(11):e2249816.
PMID: 36303448
This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and...
15.
Harrer D, Schenkel C, Berking C, Herr W, Abken H, Dorrie J, et al.
Cancers (Basel)
. 2022 Oct;
14(20).
PMID: 36291817
The addition of CAR-T cells to the armamentarium of immunotherapy revigorated the field of oncology by inducing long-lasting remissions in patients with relapsing/refractory hematological malignancies. Nevertheless, in the lion's share...
16.
Beenen A, Sauerer T, Schaft N, Dorrie J
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955729
Programmed Cell Death 1 Ligand 1 (PD-L1, CD274, B7-H1) is a transmembrane protein which is strongly involved in immune modulation, serving as checkpoint regulator. Interaction with its receptor, Programmed Cell...
17.
Lai X, Keller C, Santos G, Schaft N, Dorrie J, Vera J
Front Cell Dev Biol
. 2022 Feb;
9:746359.
PMID: 35186943
Dendritic cells (DCs) can be used for therapeutic vaccination against cancer. The success of this therapy depends on efficient tumor-antigen presentation to cytotoxic T lymphocytes (CTLs) and the induction of...
18.
Koch E, Schaft N, Kummer M, Berking C, Schuler G, Hasumi K, et al.
Front Immunol
. 2022 Feb;
13:785231.
PMID: 35185883
Uveal melanoma (UM) is an orphan disease with a mortality of 80% within one year upon the development of metastatic disease. UM does hardly respond to chemotherapy and kinase inhibitors...
19.
Strack A, Deinzer A, Thirion C, Schrodel S, Dorrie J, Sauerer T, et al.
Viruses
. 2022 Jan;
14(1).
PMID: 35062296
Due to their ability to trigger strong immune responses, adenoviruses (HAdVs) in general and the serotype5 (HAdV-5) in particular are amongst the most popular viral vectors in research and clinical...
20.
Sauerer T, Lischer C, Weich A, Berking C, Vera J, Dorrie J
Front Microbiol
. 2022 Jan;
12:785662.
PMID: 35003017
Merkel cell carcinoma (MCC) is a rare and highly aggressive cancer, which is mainly caused by genomic integration of the Merkel cell polyomavirus and subsequent expression of a truncated form...