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Jan Abendroth

Explore the profile of Jan Abendroth including associated specialties, affiliations and a list of published articles. Areas
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Articles 95
Citations 1317
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Recent Articles
21.
Mandel C, Yang H, Buchko G, Abendroth J, Grieshaber N, Chiarelli T, et al.
Pathog Dis . 2022 Apr; 80(1). PMID: 35388904
Chlamydia trachomatis is a bacterial obligate intracellular parasite and a significant cause of human disease, including sexually transmitted infections and trachoma. The bacterial RNA polymerase-binding protein DksA is a transcription...
22.
Abendroth J, Buchko G, Liew F, Nguyen J, Kim H
Biochemistry . 2022 Mar; 61(7):563-574. PMID: 35315646
The ammonia-oxidizing bacterium expresses two cytochromes in the P460 superfamily that are predicted to be structurally similar. In one, cytochrome (cyt) P460, the substrate hydroxylamine (NHOH) is converted to nitric...
23.
Iwasaki J, Lorimer D, Vivoli-Vega M, Kibble E, Peacock C, Abendroth J, et al.
J Antimicrob Chemother . 2022 Mar; 77(6):1625-1634. PMID: 35245364
Background: The macrophage infectivity potentiator (Mip) protein, which belongs to the immunophilin superfamily, is a peptidyl-prolyl cis/trans isomerase (PPIase) enzyme. Mip has been shown to be important for virulence in...
24.
Beard D, Bristol S, Cosby K, Davis A, Manning C, Perry L, et al.
Acta Crystallogr F Struct Biol Commun . 2022 Mar; 78(Pt 3):143. PMID: 35234140
The name of one of the authors in Beard et al. [(2022), Acta Cryst. F78, 59-65] is corrected.
25.
Maddy J, Staker B, Subramanian S, Abendroth J, Edwards T, Myler P, et al.
Acta Crystallogr F Struct Biol Commun . 2022 Mar; 78(Pt 3):135-142. PMID: 35234139
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections globally and is one of the most commonly reported infections in the United States. There is a need to...
26.
Beard D, Bristol S, Cosby K, Davis A, Manning C, Perry L, et al.
Acta Crystallogr F Struct Biol Commun . 2022 Feb; 78(Pt 2):59-65. PMID: 35102894
Giardiasis is the most prevalent diarrheal disease globally and affects humans and animals. It is a significant problem in developing countries, the number one cause of travelers' diarrhea and affects...
27.
Beard D, Subramanian S, Abendroth J, Dranow D, Edwards T, Myler P, et al.
Acta Crystallogr F Struct Biol Commun . 2022 Feb; 78(Pt 2):45-51. PMID: 35102892
Burkholderia pseudomallei infection causes melioidosis, which is often fatal if untreated. There is a need to develop new and more effective treatments for melioidosis. This study reports apo and cofactor-bound...
28.
Kesari P, Deshmukh A, Pahelkar N, Suryawanshi A, Rathore I, Mishra V, et al.
Protein Sci . 2022 Jan; 31(4):882-899. PMID: 35048450
Plasmodium falciparum plasmepsin X (PfPMX), involved in the invasion and egress of this deadliest malarial parasite, is essential for its survival and hence considered as an important drug target. We...
29.
Demars A, Vitali A, Comein A, Carlier E, Azouz A, Goriely S, et al.
PLoS Pathog . 2021 Sep; 17(9):e1009887. PMID: 34525130
Brucellosis is one of the most widespread bacterial zoonoses worldwide. Here, our aim was to identify the effector mechanisms controlling the early stages of intranasal infection with Brucella in C57BL/6...
30.
Jezewski A, Alden K, Esan T, DeBouver N, Abendroth J, Bullen J, et al.
ACS Chem Biol . 2021 Aug; 16(8):1587-1599. PMID: 34369755
Acetyl CoA synthetases (ACSs) are cyl-CoA/RPS/uciferase (ANL) superfamily enzymes that couple acetate with CoA to generate acetyl CoA, a key component of central carbon metabolism in eukaryotes and prokaryotes. Normal...