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Jamil S Saad

Explore the profile of Jamil S Saad including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 1414
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Recent Articles
1.
Lampel A, Bram Y, Ezer A, Shaltiel-Karyo R, Saad J, Bacharach E, et al.
ACS Chem Biol . 2024 Nov; 19(12):2594. PMID: 39607374
No abstract available.
2.
Ganaie F, Saad J, Lo S, McGee L, Bentley S, van Tonder A, et al.
J Clin Microbiol . 2024 Nov; 63(1):e0175624. PMID: 39601578
No abstract available.
3.
Herrmann D, Meng S, Yang H, Mansky L, Saad J
Viruses . 2024 Oct; 16(10). PMID: 39459862
Retroviral assembly is a highly coordinated step in the replication cycle. The process is initiated when the newly synthesized Gag and Gag-Pol polyproteins are directed to the inner leaflet of...
4.
Ganaie F, Saad J, Lo S, McGee L, van Tonder A, Hawkins P, et al.
J Biol Chem . 2023 Jul; 299(9):105085. PMID: 37495106
The polysaccharide (PS) capsule is essential for immune evasion and virulence of Streptococcus pneumoniae. Existing pneumococcal vaccines are designed to elicit anticapsule antibodies; however, the effectiveness of these vaccines is...
5.
Ganaie F, Saad J, Lo S, McGee L, Bentley S, van Tonder A, et al.
J Clin Microbiol . 2023 Mar; 61(4):e0002423. PMID: 36971549
Streptococcus pneumoniae can produce a wide breadth of antigenically diverse capsule types, a fact that poses a looming threat to the success of vaccines that target pneumococcal polysaccharide (PS) capsule....
6.
Ghanam R, Eastep G, Saad J
J Mol Biol . 2022 Nov; 435(2):167880. PMID: 36370804
Human immunodeficiency virus type 1 (HIV-1) trans-activator of transcription (Tat) is a small, intrinsically disordered basic protein that plays diverse roles in the HIV-1 replication cycle, including promotion of efficient...
7.
Samal A, Green T, Saad J
Proc Natl Acad Sci U S A . 2022 Jun; 119(23):e2200794119. PMID: 35658080
During the late phase of HIV type 1 (HIV-1) infection cycle, the virally encoded Gag polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly, formation...
8.
Herrmann D, Hanson H, Zhou L, Addabbo R, Willkomm N, Angert I, et al.
J Mol Biol . 2022 May; 434(12):167609. PMID: 35490898
Assembly of human T-cell leukemia virus type 1 (HTLV-1) particles is initiated by the trafficking of virally encoded Gag polyproteins to the inner leaflet of the plasma membrane (PM). Gag-PM...
9.
Zhang L, Kent J, Whitaker M, Young D, Herrmann D, Aleshin A, et al.
Nat Commun . 2022 Apr; 13(1):2255. PMID: 35474308
Iron is essential for growth of Mycobacterium tuberculosis, the causative agent of tuberculosis. To acquire iron from the host, M. tuberculosis uses the siderophores called mycobactins and carboxymycobactins. Here, we...
10.
Im H, Kruckow K, DMello A, Ganaie F, Martinez E, Luck J, et al.
Infect Immun . 2021 Nov; 90(1):e0045121. PMID: 34748366
Streptococcus pneumoniae colonizes the nasopharynx asymptomatically but can also cause severe life-threatening disease. Importantly, stark differences in carbohydrate availability exist between the nasopharynx and invasive disease sites, such as the...