Jamie J L Williams
Overview
Explore the profile of Jamie J L Williams including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
211
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Williams J, Baillie G, Palmer T
Methods Mol Biol
. 2020 Jun;
2169:105-118.
PMID: 32548823
The ability of inducible regulator suppressor of cytokine signaling 3 (SOCS3) to inhibit Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling requires interaction with specific cytokine receptors, JAKs, and...
2.
Durham G, Williams J, Nasim M, Palmer T
Trends Pharmacol Sci
. 2019 Apr;
40(5):298-308.
PMID: 30948191
Defective regulation of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) signalling pathway in cancers, haematological diseases, and chronic inflammatory conditions highlights its clinical significance. While several biologic and...
3.
Williams J, Alotaiq N, Mullen W, Burchmore R, Liu L, Baillie G, et al.
Nat Commun
. 2018 Jan;
9(1):168.
PMID: 29330478
Effective suppression of JAK-STAT signalling by the inducible inhibitor "suppressor of cytokine signalling 3" (SOCS3) is essential for limiting signalling from cytokine receptors. Here we show that cavin-1, a component...
4.
Speirs C, Williams J, Riches K, Salt I, Palmer T
Pharmacol Res
. 2017 Oct;
128:88-100.
PMID: 29037480
Exaggerated Janus kinase-signal transducer and activator of transcription (JAK-STAT) signalling is key to the pathogenesis of pro-inflammatory disorders, such as rheumatoid arthritis and cardiovascular diseases. Mutational activation of JAKs is...
5.
Rutherford C, Speirs C, Williams J, Ewart M, Mancini S, Hawley S, et al.
Sci Signal
. 2016 Dec;
9(453):ra109.
PMID: 27919027
Adenosine 5'-monophosphate-activated protein kinase (AMPK) is a pivotal regulator of metabolism at cellular and organismal levels. AMPK also suppresses inflammation. We found that pharmacological activation of AMPK rapidly inhibited the...
6.
Williams J, Munro K, Palmer T
Cells
. 2014 Jun;
3(2):546-62.
PMID: 24886706
The realisation that unregulated activation of the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway is a key driver of a wide range of diseases has identified its components...
7.
Williams J, Palmer T
Biochem Soc Trans
. 2014 Mar;
42(2):284-8.
PMID: 24646232
Caveolae are curved lipid raft regions rich in cholesterol and sphingolipids found abundantly in vascular endothelial cells, adipocytes, smooth muscle cells and fibroblasts. They are multifunctional organelles with roles in...
8.
Williams J, Palmer T
Biochem Soc Trans
. 2012 Jan;
40(1):215-8.
PMID: 22260693
The anti-inflammatory effects of the prototypical second messenger cAMP have been extensively documented in multiple cell types. One mechanism by which these effects are achieved is via Epac1 (exchange protein...