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James P Calvet

Explore the profile of James P Calvet including associated specialties, affiliations and a list of published articles. Areas
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Articles 73
Citations 1635
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Recent Articles
1.
Sinha S, Dwivedi N, Tao S, Jamadar A, Kakade V, O Neil M, et al.
Oncogene . 2025 Jan; 44(9):632-633. PMID: 39870786
No abstract available.
2.
Agborbesong E, Zhou J, Zhang H, Li L, Harris P, Calvet J, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892227
The primary cilium is a microtubule-based sensory organelle that plays a critical role in signaling pathways and cell cycle progression. Defects in the structure and/or function of the primary cilium...
3.
Zhou J, Li L, Zhang H, Agborbesong E, Harris P, Calvet J, et al.
Kidney Int . 2024 May; 106(2):258-272. PMID: 38782200
Alteration of DNA methylation leads to diverse diseases, and the dynamic changes of DNA methylation (DNAm) on sets of CpG dinucleotides in mammalian genomes are termed "DNAm age" and "epigenetic...
4.
Agborbesong E, Zhou J, Zhang H, Li L, Harris P, Calvet J, et al.
Biomedicines . 2024 Mar; 12(3). PMID: 38540216
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder worldwide and progresses to end-stage renal disease (ESRD). However, its precise mechanism is not fully understood. In...
5.
Lea W, Winklhofer T, Zelenchuk L, Sharma M, Rossol-Allison J, Fields T, et al.
Cells . 2023 Sep; 12(17). PMID: 37681898
The gene, encoding protein polycystin-1 (PC1), is responsible for 85% of cases of autosomal dominant polycystic kidney disease (ADPKD). PC1 has been shown to be present in urinary exosome-like vesicles...
6.
Wang W, Silva L, Wang H, Kavanaugh M, Pottorf T, Allard B, et al.
Kidney Int . 2023 May; 103(6):1202. PMID: 37210199
No abstract available.
7.
Wang W, Silva L, Wang H, Kavanaugh M, Pottorf T, Allard B, et al.
Kidney Int . 2023 Jan; 103(2):429. PMID: 36681463
No abstract available.
8.
Li L, Zhang X, Zhang H, Agborbesong E, Zhou J, Calvet J, et al.
Cells . 2023 Jan; 12(1). PMID: 36611841
ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. In this study, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas...
9.
Maser R, Calvet J, Parnell S
Front Mol Biosci . 2022 Nov; 9:1035507. PMID: 36406261
Polycystin-1 (PC1) is an 11-transmembrane (TM) domain-containing protein encoded by the gene, the most frequently mutated gene leading to autosomal dominant polycystic kidney disease (ADPKD). This large (> 462 kDal)...
10.
Yu W, Wang G, Li L, Zhang H, Gui X, Zhou J, et al.
Hum Mol Genet . 2022 Nov; 32(7):1114-1126. PMID: 36322156
Autosomal dominant polycystic kidney disease (ADPKD) is driven by mutations in the PKD1 and PKD2 genes, and it is characterized by renal cyst formation, inflammation and fibrosis. Forkhead box protein...