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Julie Xia Zhou

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Articles 18
Citations 203
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Recent Articles
1.
Agborbesong E, Zhou J, Zhang H, Li L, Harris P, Calvet J, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892227
The primary cilium is a microtubule-based sensory organelle that plays a critical role in signaling pathways and cell cycle progression. Defects in the structure and/or function of the primary cilium...
2.
Zhou J, Li L, Zhang H, Agborbesong E, Harris P, Calvet J, et al.
Kidney Int . 2024 May; 106(2):258-272. PMID: 38782200
Alteration of DNA methylation leads to diverse diseases, and the dynamic changes of DNA methylation (DNAm) on sets of CpG dinucleotides in mammalian genomes are termed "DNAm age" and "epigenetic...
3.
Agborbesong E, Zhou J, Zhang H, Li L, Harris P, Calvet J, et al.
Biomedicines . 2024 Mar; 12(3). PMID: 38540216
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder worldwide and progresses to end-stage renal disease (ESRD). However, its precise mechanism is not fully understood. In...
4.
Zhou J, Cheng A, Chen L, Li L, Agborbesong E, Torres V, et al.
Cells . 2024 Mar; 13(6. PMID: 38534333
The progression of autosomal dominant polycystic kidney disease (ADPKD), an inherited kidney disease, is associated with renal interstitial inflammation and fibrosis. CD74 has been known not only as a receptor...
5.
Zhang L, Zhang H, Agborbesong E, Zhou J, Li X
Cell Death Dis . 2023 Dec; 14(12):795. PMID: 38052787
Primary cilia are microtubule-based organelles that play important roles in development and tissue homeostasis. Macrophage migration inhibitory factor (MIF) has long been recognized as a secreted cytokine in the pathogenesis...
6.
Zhou J, Torres V
Adv Kidney Dis Health . 2023 Apr; 30(3):245-260. PMID: 37088527
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of numerous kidney cysts which leads to kidney failure. ADPKD is responsible for approximately 10% of patients with kidney...
7.
Zhou J, Torres V
Kidney Int . 2023 Mar; 103(5):859-871. PMID: 36870435
Autosomal dominant polycystic kidney disease is characterized by progressive kidney cyst formation that leads to kidney failure. Tolvaptan, a vasopressin 2 receptor antagonist, is the only drug approved to treat...
8.
Li L, Zhang X, Zhang H, Agborbesong E, Zhou J, Calvet J, et al.
Cells . 2023 Jan; 12(1). PMID: 36611841
ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. In this study, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas...
9.
Zhou J, Agborbesong E, Li L, Li X
Int J Mol Sci . 2022 Dec; 23(23). PMID: 36499487
is the most common mutated gene in human cancer. Mutant p53 protein loses its tumor-suppressor properties and gains oncogenic activity. Mutant p53 is a therapeutic target in a broad range...
10.
Yu W, Wang G, Li L, Zhang H, Gui X, Zhou J, et al.
Hum Mol Genet . 2022 Nov; 32(7):1114-1126. PMID: 36322156
Autosomal dominant polycystic kidney disease (ADPKD) is driven by mutations in the PKD1 and PKD2 genes, and it is characterized by renal cyst formation, inflammation and fibrosis. Forkhead box protein...