Madhulika Sharma
Overview
Explore the profile of Madhulika Sharma including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
589
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Recent Articles
1.
Thornton M, Sommer N, McGonigle M, Kumar Ram A, Yerrathota S, Ehirim H, et al.
Dis Model Mech
. 2025 Feb;
18(2).
PMID: 39910908
Anti-retroviral therapy (ART) has decreased human immunodeficiency virus (HIV)-1-associated morbidity. However, despite ART, immune cells remain latently infected, leading to chronic inflammation and HIV-1-associated comorbidities. New strategies are needed to...
2.
Nataraj K, Schonfeld M, Rodriguez A, Sharma M, Weinman S, Tikhanovich I
Cell Mol Gastroenterol Hepatol
. 2024 Sep;
19(1):101414.
PMID: 39349250
Background & Aims: Alcohol-associated liver disease (ALD) is a major cause of alcohol-related mortality. Sex is an important variable; however, the mechanism behind sex differences is not yet established. Methods:...
3.
Tsilosani A, Gao C, Chen E, Lightle A, Shehzad S, Sharma M, et al.
J Am Soc Nephrol
. 2024 Jan;
35(4):398-409.
PMID: 38254271
Significance Statement: Autosomal dominant polycystic kidney disease (ADPKD) is a devastating disorder caused by mutations in polycystin 1 ( PKD1 ) and polycystin 2 ( PKD2 ). Currently, the mechanism...
4.
Thornton M, Sommer N, McGonigle M, Kumar Ram A, Yerrathota S, Ehirim H, et al.
bioRxiv
. 2023 Sep;
PMID: 37745500
Antiretroviral therapy (ART) has decreased HIV-1 associated morbidity. However, despite ART, immune cells remain latently infected and slowly release viral proteins, leading to chronic inflammation and HIV-1 associated comorbidities. New...
5.
Lea W, Winklhofer T, Zelenchuk L, Sharma M, Rossol-Allison J, Fields T, et al.
Cells
. 2023 Sep;
12(17).
PMID: 37681898
The gene, encoding protein polycystin-1 (PC1), is responsible for 85% of cases of autosomal dominant polycystic kidney disease (ADPKD). PC1 has been shown to be present in urinary exosome-like vesicles...
6.
Daniel E, Sommer N, Sharma M
Clin Sci (Lond)
. 2023 Aug;
137(15):1145-1150.
PMID: 37553961
Polycystic kidney disease (PKD) is a developmental disorder, which either manifests in early childhood or later in life, depending on the genetic mutation one harbors. The mechanisms of cyst initiation...
7.
Wang W, Silva L, Wang H, Kavanaugh M, Pottorf T, Allard B, et al.
Kidney Int
. 2023 May;
103(6):1202.
PMID: 37210199
No abstract available.
8.
Wang W, Silva L, Wang H, Kavanaugh M, Pottorf T, Allard B, et al.
Kidney Int
. 2023 Jan;
103(2):429.
PMID: 36681463
No abstract available.
9.
Aggarwal R, Sharma M, Singh U, Poulton K, Bhatia T, Mangat N, et al.
Ophthalmic Genet
. 2023 Jan;
44(1):1-5.
PMID: 36594723
Background: The KIR receptors present on the natural killer (NK) cells play a crucial role by exercising cytotoxicity to eliminate tumor cells. Both KIR and class-I HLA molecules exhibit extensive...
10.
Wang W, Silva L, Wang H, Kavanaugh M, Pottorf T, Allard B, et al.
Kidney Int
. 2022 Jun;
102(3):577-591.
PMID: 35644283
Primary cilia are sensory organelles built and maintained by intraflagellar transport (IFT) multiprotein complexes. Deletion of several IFT-B genes attenuates polycystic kidney disease (PKD) severity in juvenile and adult autosomal...