James McCluskey
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Explore the profile of James McCluskey including associated specialties, affiliations and a list of published articles.
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229
Citations
13306
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Recent Articles
11.
Patton T, Zhao Z, Lim X, Eddy E, Wang H, Nelson A, et al.
Cell Death Dis
. 2023 Feb;
14(2):111.
PMID: 36774342
Cell death mechanisms in T lymphocytes vary according to their developmental stage, cell subset and activation status. The cell death control mechanisms of mucosal-associated invariant T (MAIT) cells, a specialized...
12.
Wang C, Awad W, Liu L, Mak J, Veerapen N, Illing P, et al.
J Biol Chem
. 2022 Nov;
298(12):102714.
PMID: 36403855
The Major Histocompatibility Complex class I-related protein 1 (MR1) presents small molecule metabolites, drugs, and drug-like molecules that are recognized by MR1-reactive T cells. While we have an understanding of...
13.
Zhang J, Cao J, Zheng R, Yu M, Lin Z, Wang C, et al.
iScience
. 2022 Nov;
25(11):105340.
PMID: 36325063
The dynamic interaction between the CMV virus and host immune response remains obscure, thus hindering the diagnosis and therapeutic management of patients with HSCT. The current diagnosis of CMV viremia...
14.
de Lima Moreira M, Borges-Fernandes L, Pascoal-Xavier M, Lopes Ribeiro A, Pereira V, Pediongco T, et al.
Front Immunol
. 2022 Oct;
13:926446.
PMID: 36189274
Mucosal-associated invariant T (MAIT) cells are restricted by MR1 and are known to protect against bacterial and viral infections. Our understanding of the role of MAIT cells in parasitic infections,...
15.
Souter M, Awad W, Li S, Pediongco T, Meehan B, Meehan L, et al.
J Exp Med
. 2022 Aug;
219(9).
PMID: 36018322
Mucosal-associated invariant T (MAIT) cells detect microbial infection via recognition of riboflavin-based antigens presented by the major histocompatibility complex class I (MHC-I)-related protein 1 (MR1). Most MAIT cells in human...
16.
Wang H, Nelson A, Wang B, Zhao Z, Lim X, Shi M, et al.
Immunol Cell Biol
. 2022 May;
100(7):547-561.
PMID: 35514192
Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells mediating protection against bacterial infection through recognition of microbial metabolites derived from riboflavin biosynthesis. Mouse MAIT cells...
17.
Johnson D, Ruan Z, Petley E, Devi S, Holz L, Uldrich A, et al.
Sci Rep
. 2022 Mar;
12(1):4034.
PMID: 35260653
Natural Killer T (NKT) cells and Mucosal-Associated Invariant T (MAIT) cells are innate-like T cells that express semi-invariant αβ T cell receptors (TCRs) through which they recognise CD1d and MR1...
18.
Suliman S, Kjer-Nielsen L, Iwany S, Lopez Tamara K, Loh L, Grzelak L, et al.
J Immunol
. 2022 Mar;
208(6):1389-1395.
PMID: 35246495
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are highly abundant in human blood and tissues. Most MAIT cells have an invariant TCRα-chain that uses T cell receptor...
19.
Seneviratna R, Redmond S, McWilliam H, Reantragoon R, Villadangos J, McCluskey J, et al.
Immunol Cell Biol
. 2022 Feb;
100(3):218.
PMID: 35168300
No abstract available.
20.
Seneviratna R, Redmond S, McWilliam H, Reantragoon R, Villadangos J, McCluskey J, et al.
Immunol Cell Biol
. 2021 Dec;
100(2):112-126.
PMID: 34940995
MHC-related protein 1 (MR1) presents microbial riboflavin metabolites to mucosal-associated invariant T (MAIT) cells for surveillance of microbial presence. MAIT cells express a semi-invariant T-cell receptor (TCR), which recognizes MR1-antigen...