James J Knox
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Explore the profile of James J Knox including associated specialties, affiliations and a list of published articles.
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826
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Recent Articles
1.
Knox J, Karolyi K, Monslow J, Cromley D, Rader D, Pure E, et al.
J Immunol
. 2025 Mar;
PMID: 40073097
The humoral immune system influences the development of atherosclerosis, but the contributions of specific memory B cell subsets and IgG isotypes are poorly understood. We assessed the relationship between atherosclerosis...
2.
Golden G, Wu V, Hamilton J, Amses K, Shapiro M, Japp A, et al.
bioRxiv
. 2024 Sep;
PMID: 39345402
Autoimmune destruction of pancreatic β cells results in type 1 diabetes (T1D), with pancreatic immune infiltrate representing a key feature in this process. Studies of human T1D immunobiology have predominantly...
3.
Knox J, Cancro M
Immunol Cell Biol
. 2024 Mar;
102(4):229-231.
PMID: 38525813
Age-associated B cells (ABCs) are a stable subset of memory B lymphocytes that develop during microbial infections and in autoimmune diseases. Despite growing appreciation of their phenotypic and functional characteristics,...
4.
Zhang Z, Markmann C, Yu M, Agarwal D, Rostami S, Wang W, et al.
Cell Rep Med
. 2023 Dec;
4(12):101336.
PMID: 38118406
Pre-existing anti-human leukocyte antigen (HLA) allo-antibodies constitute a major barrier to transplantation. Current desensitization approaches fail due to ineffective depletion of allo-specific memory B cells (Bmems) and long-lived plasma cells...
5.
Han X, Alameh M, Butowska K, Knox J, Lundgreen K, Ghattas M, et al.
Nat Nanotechnol
. 2023 Jun;
18(9):1105-1114.
PMID: 37365276
Lipid nanoparticle (LNP)-formulated messenger RNA (mRNA) vaccineare a promising platform to prevent infectious diseases as demonstrated by the recent success of SARS-CoV-2 mRNA vaccines. To avoid immune recognition and uncontrolled...
6.
Alameh M, Tombacz I, Bettini E, Lederer K, Sittplangkoon C, Wilmore J, et al.
Immunity
. 2022 Jun;
55(6):1136-1138.
PMID: 35704995
No abstract available.
7.
Alameh M, Tombacz I, Bettini E, Lederer K, Sittplangkoon C, Wilmore J, et al.
Immunity
. 2021 Dec;
54(12):2877-2892.e7.
PMID: 34852217
Adjuvants are critical for improving the quality and magnitude of adaptive immune responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines have shown great efficacy against severe acute respiratory syndrome...
8.
Awasthi S, Knox J, Desmond A, Alameh M, Gaudette B, Lubinski J, et al.
J Clin Invest
. 2021 Oct;
131(23).
PMID: 34618692
Nucleoside-modified mRNA vaccines have gained global attention because of COVID-19. We evaluated a similar vaccine approach for preventing a chronic, latent genital infection rather than an acute respiratory infection. We...
9.
Zabaleta N, Dai W, Bhatt U, Herate C, Maisonnasse P, Chichester J, et al.
Cell Host Microbe
. 2021 Aug;
29(9):1437-1453.e8.
PMID: 34428428
The SARS-CoV-2 pandemic has affected more than 185 million people worldwide resulting in over 4 million deaths. To contain the pandemic, there is a continued need for safe vaccines that...
10.
Pyfrom S, Paneru B, Knox J, Cancro M, Posso S, Buckner J, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(24).
PMID: 34103397
Systemic lupus erythematous (SLE) is a female-predominant disease characterized by autoimmune B cells and pathogenic autoantibody production. Individuals with two or more X chromosomes are at increased risk for SLE,...