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Drew Weissman

Explore the profile of Drew Weissman including associated specialties, affiliations and a list of published articles. Areas
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Articles 233
Citations 13939
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Recent Articles
1.
Papp T, Zeng J, Shahnawaz H, Akyianu A, Breda L, Yadegari A, et al.
Mol Ther . 2025 Mar; PMID: 40087866
mRNA-based therapeutics delivered via lipid nanoparticles (LNP-mRNA) hold great promise for treating diverse diseases. However, further improvements are needed to refine outcomes in non-vaccine, extrahepatic applications, such as minimizing the...
2.
Han X, Xu Y, Ricciardi A, Xu J, Palanki R, Chowdhary V, et al.
bioRxiv . 2025 Mar; PMID: 40060499
mRNA-based gene editing therapeutics offer the potential to permanently cure diseases but are hindered by suboptimal delivery platforms. Here, we devise a robust combinatorial chemistry for plug-and-play assembly of diverse...
3.
Blizard G, Dwivedi G, Pan Y, Hou C, Etersque J, Said H, et al.
Nat Commun . 2025 Mar; 16(1):2234. PMID: 40044669
Noninvasive visualization of the distribution and persistence of mRNA vaccine antigen expression in mammalian systems has implications for the development and evaluation of future mRNA vaccines. Here, we genetically fuse...
4.
Connors J, Joyner D, Mege N, Cusimano G, Bell M, Marcy J, et al.
Commun Biol . 2025 Feb; 8(1):285. PMID: 39987408
No abstract available.
5.
Meshanni J, Stevenson E, Zhang D, Sun R, Ona N, Reagan E, et al.
Nat Commun . 2025 Feb; 16(1):1806. PMID: 39984450
Current clinical strategies for the delivery of pulmonary therapeutics to the lung are primarily targeted to the upper portions of the airways, such as treatment with nebulized instillation and inhalation....
6.
Hofbauer S, Fink L, Young R, Vijayakumar T, Nelson K, Bellopede N, et al.
bioRxiv . 2025 Feb; PMID: 39974923
During pregnancy, the maternal immune system adapts to balance tolerance of the semi-allogenic fetus while protecting the fetus from pathogens. Dysregulated immune activity at the maternal-fetal interface contributes to pregnancy...
7.
Yanik S, Venkatesh V, Gordy J, Alameh M, Meza J, Li Y, et al.
NPJ Vaccines . 2025 Feb; 10(1):34. PMID: 39971939
Malaria resurgence in 2022 saw 249 million clinical cases and 608,000 deaths, mostly in children under five. The WHO-approved circumsporozoite protein (CSP)-targeting vaccines, RTS,S and R21, remain limited in availability....
8.
Swingle K, Hamilton A, Safford H, Geisler H, Thatte A, Palanki R, et al.
Nature . 2025 Feb; 638(8051):E33. PMID: 39900626
No abstract available.
9.
Phan A, Aunins E, Cruz-Morales E, Dwivedi G, Bunkofske M, Eberhard J, et al.
bioRxiv . 2025 Feb; PMID: 39896632
The ability of lipid nanoparticle (LNP)-delivered mRNA vaccines to induce type I IFNs is critical to promote CD8 T cell responses. The studies presented here indicate that immunization with nucleoside...
10.
Banda O, Adams S, Omer L, Jung S, Said H, Phoka T, et al.
Mol Ther Nucleic Acids . 2025 Jan; 36(1):102423. PMID: 39811495
Fanconi anemia (FA) is a congenital multisystem disorder characterized by early-onset bone marrow failure (BMF) and cancer susceptibility. While gene addition and repair therapies are being considered as treatment options,...