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David Allman

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Articles 94
Citations 4587
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Recent Articles
1.
Allman A, Gaudette B, Kelly S, Alouche N, Carrington L, Perkey E, et al.
Immunity . 2024 Dec; 58(1):143-161.e8. PMID: 39731910
Innate-like splenic marginal zone (MZ) B (MZB) cells play unique roles in immunity due to their rapid responsiveness to blood-borne microbes. How MZB cells integrate cell-extrinsic and -intrinsic processes to...
2.
Banerjee S, Sanyal S, Hodawadekar S, Naiyer S, Bano N, Banerjee A, et al.
Genes Dev . 2024 Oct; 38(17-20):887-914. PMID: 39362773
During B-cell development, cells progress through multiple developmental stages, with the pro-B-cell stage defining commitment to the B-cell lineage. YY1 is a ubiquitous transcription factor that is capable of both...
3.
Hasanali Z, Garfall A, Burzenski L, Shultz L, Tang Y, Kadu S, et al.
JCI Insight . 2024 May; 9(10). PMID: 38713510
Multiple myeloma is a largely incurable and life-threatening malignancy of antibody-secreting plasma cells. An effective and widely available animal model that recapitulates human myeloma and related plasma cell disorders is...
4.
Banerjee S, Sanyal S, Hodawadekar S, Naiyer S, Bano N, Banerjee A, et al.
bioRxiv . 2024 Apr; PMID: 38586061
During B cell development, cells progress through multiple developmental stages with the pro-B cell stage defining commitment to the B cell lineage. YY1 is a ubiquitous transcription factor that is...
5.
Ishikawa M, Hasanali Z, Zhao Y, Das A, Lavaert M, Roman C, et al.
Nature . 2024 Feb; 626(8001):1102-1107. PMID: 38355795
Plasma cells produce large quantities of antibodies and so play essential roles in immune protection. Plasma cells, including a long-lived subset, reside in the bone marrow where they depend on...
6.
Hasanali Z, Garfall A, Burzenski L, Shultz L, Tang Y, Kadu S, et al.
bioRxiv . 2024 Feb; PMID: 38328086
Multiple myeloma is a largely incurable and life-threatening malignancy of antibody-secreting plasma cells. An effective and widely available animal model that recapitulates human myeloma and related plasma cell disorders is...
7.
Zhang Z, Markmann C, Yu M, Agarwal D, Rostami S, Wang W, et al.
Cell Rep Med . 2023 Dec; 4(12):101336. PMID: 38118406
Pre-existing anti-human leukocyte antigen (HLA) allo-antibodies constitute a major barrier to transplantation. Current desensitization approaches fail due to ineffective depletion of allo-specific memory B cells (Bmems) and long-lived plasma cells...
8.
Bracchi-Ricard V, Nguyen K, Ricci D, Gaudette B, Henao-Mejia J, Brambilla R, et al.
FASEB J . 2023 Nov; 37(12):e23283. PMID: 37983957
Activation of the endoplasmic reticulum (ER) stress sensor inositol-requiring enzyme-1α (IRE1α) contributes to neuronal development and is known to induce neuronal remodeling in vitro and in vivo. On the contrary,...
9.
Malin J, Martinez-Ruiz G, Zhao Y, Shissler S, Cowan J, Ding Y, et al.
Sci Adv . 2023 Nov; 9(46):eadg8126. PMID: 37967174
Thymic epithelial cells (TEC) control T cell development and play essential roles in establishing self-tolerance. By using -driven ablation of gene in TEC, we identified as a critical factor in...
10.
Ochoa T, Rossi A, Woodle E, Hildeman D, Allman D
J Immunol . 2023 Nov; 212(1):154-164. PMID: 37966267
The proteasome inhibitor bortezomib (BTZ) is proposed to deplete activated B cells and plasma cells. However, a complete picture of the mechanisms underlying BTZ-induced apoptosis in B lineage cells remains...