James H Shelhamer
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Explore the profile of James H Shelhamer including associated specialties, affiliations and a list of published articles.
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43
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3511
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Recent Articles
11.
Baird K, Steinberg S, Grkovic L, Pulanic D, Cowen E, Mitchell S, et al.
Biol Blood Marrow Transplant
. 2013 Jan;
19(4):632-9.
PMID: 23340040
Between 2004 and 2010, 189 adult patients were enrolled on the National Cancer Institute's cross-sectional chronic graft-versus-host disease (cGVHD) natural history study. Patients were evaluated by multiple disease scales and...
12.
Klionsky D, Abdalla F, Abeliovich H, Abraham R, Acevedo-Arozena A, Adeli K, et al.
Autophagy
. 2012 Sep;
8(4):445-544.
PMID: 22966490
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered...
13.
Qi H, Daniels M, Liu Y, Chen L, Alsaaty S, Levine S, et al.
J Immunol
. 2011 Oct;
187(10):5286-92.
PMID: 22003202
Autophagy delivers cytoplasmic constituents to autophagosomes and is involved in innate and adaptive immunity. Cytosolic phospholipase (cPLA(2))-initiated proinflammatory lipid mediator pathways play a critical role in host defense and inflammation....
14.
Eberlein M, Permutt S, Chahla M, Bolukbas S, Nathan S, Shlobin O, et al.
Chest
. 2011 Jul;
141(2):451-460.
PMID: 21799025
Background: Size mismatch between donor lungs and a recipient thorax could affect the major determinants of maximal expiratory airflow: airway resistance, propensity of airways to collapse, and lung elastic recoil....
15.
Shah N, Tulapurkar M, Singh I, Shelhamer J, Cowan M, Hasday J
Prostaglandins Other Lipid Mediat
. 2010 Apr;
93(1-2):1-7.
PMID: 20382255
The heat shock (HS) response is an important cytoprotective response comprising the expression of heat shock proteins (HSPs) and orchestrated by the heat/stress-induced transcription factor, heat shock factor-1 (HSF-1). Previous...
16.
Woszczek G, Chen L, Alsaaty S, Nagineni S, Shelhamer J
J Immunol
. 2010 Jan;
184(4):2219-25.
PMID: 20083671
The use of cysteinyl leukotriene receptor antagonists (LTRAs) for asthma therapy has been associated with a significant degree of interpatient variability in response to treatment. Some of that variability may...
17.
Chen L, Woszczek G, Nagineni S, Logun C, Shelhamer J
Am J Physiol Lung Cell Mol Physiol
. 2008 May;
295(2):L326-35.
PMID: 18502815
Cytosolic phospholipase A(2)alpha (cPLA(2)alpha) activation is a regulatory step in the control of arachidonic acid (AA) liberation for eicosanoid formation. Sphingosine 1-phosphate (S1P) is a bioactive lipid mediator involved in...
18.
Woszczek G, Chen L, Nagineni S, Shelhamer J
J Immunol
. 2008 May;
180(11):7597-603.
PMID: 18490762
The immunoregulatory cytokine IL-10 plays an essential role in down-modulating adaptive and innate immune responses leading to chronic inflammatory diseases. In contrast, cysteinyl leukotrienes (cysLTs), important proinflammatory mediators of cell...
19.
Woszczek G, Chen L, Nagineni S, Kern S, Barb J, Munson P, et al.
J Allergy Clin Immunol
. 2007 Nov;
121(1):215-221.e1.
PMID: 18028998
Background: Cysteinyl leukotrienes (CysLTs) are important mediators of innate immune responsiveness and chronic inflammatory diseases. CysLTs acting through CysLT receptors can influence the migration and activity of cells, such as...
20.
Woszczek G, Chen L, Nagineni S, Alsaaty S, Harry A, Logun C, et al.
J Immunol
. 2007 Apr;
178(8):5262-70.
PMID: 17404310
Cysteinyl leukotrienes (cysLTs) are important mediators of cell trafficking and innate immune responses, involved in the pathogenesis of inflammatory processes, i.e., atherosclerosis, pulmonary fibrosis, and bronchial asthma. The aim of...