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Sara Alsaaty

Explore the profile of Sara Alsaaty including associated specialties, affiliations and a list of published articles. Areas
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Citations 292
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Recent Articles
1.
Sokolowska M, Chen L, Liu Y, Martinez-Anton A, Logun C, Alsaaty S, et al.
J Allergy Clin Immunol . 2016 Nov; 139(4):1379-1383. PMID: 27826094
No abstract available.
2.
Davis A, Chertow D, Kindrachuk J, Qi L, Schwartzman L, Suzich J, et al.
Virology . 2016 Apr; 493:238-46. PMID: 27062579
The 1918 influenza pandemic caused ~50 million deaths. Many questions remain regarding the origin, pathogenicity, and mechanisms of human adaptation of this virus. Avian-adapted influenza A viruses preferentially bind α2,3-linked...
3.
Sokolowska M, Chen L, Liu Y, Martinez-Anton A, Qi H, Logun C, et al.
J Immunol . 2015 Apr; 194(11):5472-5487. PMID: 25917098
PGE2 is a potent lipid mediator involved in maintaining homeostasis but also promotion of acute inflammation or immune suppression in chronic inflammation and cancer. Nucleotide-binding domain, leucine-rich repeat-containing protein (NLR)P3...
4.
Liu Y, Chen L, Sokolowska M, Eberlein M, Alsaaty S, Martinez-Anton A, et al.
Immunology . 2014 Mar; 143(1):81-95. PMID: 24673159
Docosahexaenoic acid (DHA) is one of the major ingredients of fish oil and has been reported to have anti-inflammatory properties mediated through the GPR120 receptor. Whether cytosolic phospholipase A2 (cPLA2...
5.
Sokolowska M, Chen L, Eberlein M, Martinez-Anton A, Liu Y, Alsaaty S, et al.
J Biol Chem . 2013 Dec; 289(7):4470-88. PMID: 24366870
Hyaluronan (HA) is the major glycosaminoglycan in the extracellular matrix. During inflammation, there is an increased breakdown of HA, resulting in the accumulation of low molecular weight (LMW) HA and...
6.
Martinez-Anton A, Sokolowska M, Kern S, Davis A, Alsaaty S, Taubenberger J, et al.
Am J Respir Cell Mol Biol . 2013 Apr; 49(3):384-95. PMID: 23590309
We studied the changes in expression of microRNAs (miRNAs or miRs) and mRNA in normal human bronchial epithelial cells as they differentiate from an undifferentiated monolayer to a differentiated pseudostratified...
7.
Qi H, Daniels M, Liu Y, Chen L, Alsaaty S, Levine S, et al.
J Immunol . 2011 Oct; 187(10):5286-92. PMID: 22003202
Autophagy delivers cytoplasmic constituents to autophagosomes and is involved in innate and adaptive immunity. Cytosolic phospholipase (cPLA(2))-initiated proinflammatory lipid mediator pathways play a critical role in host defense and inflammation....
8.
Woszczek G, Chen L, Alsaaty S, Nagineni S, Shelhamer J
J Immunol . 2010 Jan; 184(4):2219-25. PMID: 20083671
The use of cysteinyl leukotriene receptor antagonists (LTRAs) for asthma therapy has been associated with a significant degree of interpatient variability in response to treatment. Some of that variability may...
9.
Deans K, Minneci P, Chen H, Kern S, Logun C, Alsaaty S, et al.
BMC Genomics . 2009 Jun; 10:280. PMID: 19552812
Background: The expression levels of many genes show wide natural variation among strains or populations. This study investigated the potential for animal strain-related genotypic differences to confound gene expression profiles...
10.
Woszczek G, Chen L, Nagineni S, Alsaaty S, Harry A, Logun C, et al.
J Immunol . 2007 Apr; 178(8):5262-70. PMID: 17404310
Cysteinyl leukotrienes (cysLTs) are important mediators of cell trafficking and innate immune responses, involved in the pathogenesis of inflammatory processes, i.e., atherosclerosis, pulmonary fibrosis, and bronchial asthma. The aim of...