James H Morrissey
Overview
Explore the profile of James H Morrissey including associated specialties, affiliations and a list of published articles.
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130
Citations
3641
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Recent Articles
1.
Muller M, Mortenson A, Sedzro J, Wen P, Morrissey J, Tajkhorshid E
Blood Adv
. 2024 Dec;
9(4):729-740.
PMID: 39671302
Formation of the extrinsic complex (EC) on cell surfaces is the event that triggers the coagulation cascade. Tissue factor (TF) and factor VIIa (FVIIa) form the EC together with FX...
2.
Sedzro J, Smith S, Scott A, Wang Y, Travers R, Hemp R, et al.
Res Pract Thromb Haemost
. 2024 Sep;
8(6):102550.
PMID: 39309228
Background: Inorganic polyphosphates (polyPs) are linear chains of phosphates that accelerate blood clotting. Targeting polyP has been shown to reduce thrombosis. Objectives: To identify and characterize anti-polyP monoclonal antibodies that...
3.
Morrissey J
Arterioscler Thromb Vasc Biol
. 2024 Jun;
44(7):1671-1673.
PMID: 38924441
No abstract available.
4.
MacArthur T, Goswami J, Navarro S, Vappala S, La C, Yudin N, et al.
Shock
. 2024 Apr;
61(6):848-854.
PMID: 38662595
Background: Inorganic polyphosphate (polyP) is a procoagulant polyanion. We assessed the impact of polyP inhibition on thrombin generation after trauma using the novel polyP antagonists, macromolecular polyanion inhibitor 8 (MPI...
5.
La C, Smith S, Kalathottukaren M, Haynes C, Morrissey J, Kizhakkedathu J
Adv Healthc Mater
. 2024 Mar;
13(20):e2400108.
PMID: 38537246
Thrombosis, the formation of blood clots within a blood vessel, can lead to severe complications including pulmonary embolism, cardiac arrest, and stroke. The most widely administered class of anticoagulants is...
6.
Hajeyah A, Protty M, Paul D, Costa D, Omidvar N, Morgan B, et al.
J Lipid Res
. 2023 Dec;
65(1):100484.
PMID: 38103786
Aminophospholipids (aPL) such as phosphatidylserine are essential for supporting the activity of coagulation factors, circulating platelets, and blood cells. Phosphatidylthreonine (PT) is an aminophospholipid previously reported in eukaryotic parasites and...
7.
Lillicrap D, Morrissey J
J Thromb Haemost
. 2023 Nov;
21(12):3285-3286.
PMID: 38000849
No abstract available.
8.
Cheng K, De Lio A, Jain R, Paul D, Morrissey J, Pogorelov T
Biochemistry
. 2023 Sep;
62(20):3020-3032.
PMID: 37747791
Protein binding to negatively charged lipids is essential for maintaining numerous vital cellular processes where its dysfunction can lead to various diseases. One such protein that plays a crucial role...
9.
Lillicrap D, Morrissey J
J Thromb Haemost
. 2023 Jul;
21(8):2005-2006.
PMID: 37468172
No abstract available.
10.
Vappala S, Smith S, Kizhakkedathu J, Morrissey J
Semin Thromb Hemost
. 2023 May;
50(7):970-977.
PMID: 37192652
The contact pathway of blood clotting has received intense interest in recent years as studies have linked it to thrombosis, inflammation, and innate immunity. Because the contact pathway plays little...