James H Catterson
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Explore the profile of James H Catterson including associated specialties, affiliations and a list of published articles.
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11
Citations
213
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Recent Articles
1.
Catterson J, Mouofo E, Lopez De Toledo Soler I, Lean G, Dlamini S, Liddell P, et al.
Brain Commun
. 2024 Aug;
6(4):fcae256.
PMID: 39130515
Alzheimer's disease is the most common cause of dementia in the elderly, prompting extensive efforts to pinpoint novel therapeutic targets for effective intervention. Among the hallmark features of Alzheimer's disease...
2.
Zhang P, Catterson J, Gronke S, Partridge L
Nat Aging
. 2024 Feb;
4(4):491-509.
PMID: 38413780
Suppression of target of rapamycin complex 1 (TORC1) by rapamycin ameliorates aging in diverse species. S6 kinase (S6K) is an essential mediator, but the mechanisms involved are unclear. Here we...
3.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, Tulloch J, et al.
Acta Neuropathol
. 2024 Feb;
147(1):32.
PMID: 38319380
Synapse loss correlates with cognitive decline in Alzheimer's disease, and soluble oligomeric amyloid beta (Aβ) is implicated in synaptic dysfunction and loss. An important knowledge gap is the lack of...
4.
Taylor L, Simzer E, Pimblett C, Lacey-Solymar O, McGeachan R, Meftah S, et al.
Acta Neuropathol
. 2024 Jan;
147(1):7.
PMID: 38175261
Tau hyperphosphorylation and aggregation is a common feature of many dementia-causing neurodegenerative diseases. Tau can be phosphorylated at up to 85 different sites, and there is increasing interest in whether...
5.
Catterson J, Minkley L, Aspe S, Judd-Mole S, Moura S, Dyson M, et al.
Neurobiol Aging
. 2023 Oct;
132:154-174.
PMID: 37837732
Amyloid β (Aβ) accumulation is a hallmark of Alzheimer's disease. In adult Drosophila brains, human Aβ overexpression harms climbing and lifespan. It's uncertain whether Aβ is intrinsically toxic or activates...
6.
Regan J, Lu Y, Urena E, Meilenbrock R, Catterson J, Kissler D, et al.
Nat Aging
. 2023 Apr;
2(12):1145-1158.
PMID: 37118538
Pharmacological attenuation of mTOR presents a promising route for delay of age-related disease. Here we show that treatment of Drosophila with the mTOR inhibitor rapamycin extends lifespan in females, but...
7.
Catterson J, Khericha M, Dyson M, Vincent A, Callard R, Haveron S, et al.
Curr Biol
. 2018 May;
28(11):1714-1724.e4.
PMID: 29779873
Intermittent fasting (IF) can improve function and health during aging in laboratory model organisms, but the mechanisms at work await elucidation. We subjected fruit flies (Drosophila melanogaster) to varying degrees...
8.
Ivy J, Drechsler M, Catterson J, Bodmer R, Ocorr K, Paululat A, et al.
PLoS One
. 2015 Aug;
10(8):e0134620.
PMID: 26301956
Insect nephrocytes are highly endocytic scavenger cells that represent the only invertebrate model for the study of human kidney podocytes. Despite their importance, nephrocyte development is largely uncharacterised. This work...
9.
Catterson J, Heck M, Hartley P
PLoS One
. 2013 May;
8(5):e62958.
PMID: 23690969
The vertebrate Kindlins are an evolutionarily conserved family of proteins critical for integrin signalling and cell adhesion. Kindlin-2 (KIND2) is associated with intercalated discs in mice, suggesting a role in...
10.
Dear J, Simpson K, Nicolai M, Catterson J, Street J, Huizinga T, et al.
J Immunol
. 2011 Aug;
187(6):3347-52.
PMID: 21824865
The immune system is alerted to cell death by molecules known as damage-associated molecular patterns (DAMPs). These molecules partly mediate acetaminophen-induced liver injury, an archetypal experimental model of sterile cell...