James C Williamson
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Explore the profile of James C Williamson including associated specialties, affiliations and a list of published articles.
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36
Citations
1348
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Recent Articles
1.
Bertlin J, Pauzaite T, Liang Q, Wit N, Williamson J, Sia J, et al.
bioRxiv
. 2024 Sep;
PMID: 39282259
Clear cell renal cell carcinoma (ccRCC) represents the most common form of kidney cancer and is typified by biallelic inactivation of the von Hippel-Lindau () tumour suppressor gene. Here, we...
2.
McKie S, Nicholson A, Smith E, Fawke S, Caroe E, Williamson J, et al.
Proc Natl Acad Sci U S A
. 2023 Mar;
120(14):e2218823120.
PMID: 36996106
Myelin is a multilayered membrane that tightly wraps neuronal axons, enabling efficient, high-speed signal propagation. The axon and myelin sheath form tight contacts, mediated by specific plasma membrane proteins and...
3.
Crozier T, Greenwood E, Williamson J, Guo W, Porter L, Gabaev I, et al.
Wellcome Open Res
. 2022 Dec;
7:224.
PMID: 36483314
Quantitative proteomics is able to provide a comprehensive, unbiased description of changes to cells caused by viral infection, but interpretation may be complicated by differential changes in infected and uninfected...
4.
Randzavola L, Mortimer P, Garside E, Dufficy E, Schejtman A, Roumelioti G, et al.
Elife
. 2022 Nov;
11.
PMID: 36421765
EROS (essential for reactive oxygen species) protein is indispensable for expression of gp91, the catalytic core of the phagocyte NADPH oxidase. EROS deficiency in humans is a novel cause of...
5.
Volkmar N, Gawden-Bone C, Williamson J, Nixon-Abell J, West J, George-Hyslop P, et al.
EMBO J
. 2022 Aug;
41(19):e110777.
PMID: 35993436
The regulation of membrane lipid composition is critical for cellular homeostasis. Cells are particularly sensitive to phospholipid saturation, with increased saturation causing membrane rigidification and lipotoxicity. How mammalian cells sense...
6.
Fielding C, Sabberwal P, Williamson J, Greenwood E, Crozier T, Zelek W, et al.
Elife
. 2022 May;
11.
PMID: 35587364
The outcome of infection is dependent on the ability of viruses to manipulate the infected cell to evade immunity, and the ability of the immune response to overcome this evasion....
7.
Anderson G, Ballester-Beltran J, Giotopoulos G, Guerrero J, Surget S, Williamson J, et al.
Blood
. 2022 Feb;
139(16):2471-2482.
PMID: 35134130
The accessibility of cell surface proteins makes them tractable for targeting by cancer immunotherapy, but identifying suitable targets remains challenging. Here we describe plasma membrane profiling of primary human myeloma...
8.
Boggess T, Williamson J, Niebergall E, Sexton H, Mazur A, Egleton R, et al.
Front Pediatr
. 2021 Dec;
9:794544.
PMID: 34966707
The rise in rates of opioid abuse in recent years in the United States has led to a dramatic increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved...
9.
Cerny O, Godlee C, Tocci R, Cross N, Shi H, Williamson J, et al.
PLoS Pathog
. 2021 Jul;
17(7):e1009771.
PMID: 34314469
The Salmonella enterica effector SteD depletes mature MHC class II (mMHCII) molecules from the surface of infected antigen-presenting cells through ubiquitination of the cytoplasmic tail of the mMHCII β chain....
10.
Mazur A, Bills E, DeSchepper K, Williamson J, Henderson B, Risher W
eNeuro
. 2021 Jul;
8(4).
PMID: 34266964
The regulation of synaptic connectivity in the brain is vital to proper functioning and development of the CNS. Formation of neural networks in the CNS has been shown to be...