Jaime Perez-Villanueva
Overview
Explore the profile of Jaime Perez-Villanueva including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
170
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Recent Articles
1.
Olascoaga S, Konigsberg M, Espinal-Enriquez J, Tovar H, Matadamas-Martinez F, Perez-Villanueva J, et al.
FEBS J
. 2025 Jan;
PMID: 39871113
Cellular senescence is an irreversible cell cycle arrest caused by various stressors that damage cells. Over time, senescent cells accumulate and contribute to the progression of multiple age-related degenerative diseases....
2.
Del Carmen Navarrete-Mondragon R, Cortes-Benitez F, Elena Mendieta-Wejebe J, Gonzalez-Andrade M, Perez-Villanueva J
ChemMedChem
. 2024 Aug;
19(23):e202400452.
PMID: 39113101
Current treatments for type 2 diabetes (T2D) mainly rely on exercise, dietary control, and anti-diabetic drugs to enhance insulin secretion and improve insulin sensitivity. However, there is a need for...
3.
Mendoza-Jasso M, Perez-Villanueva J, Alvarado-Rodriguez J, Gonzalez-Andrade M, Cortes-Benitez F
ACS Omega
. 2024 Aug;
9(30):33224-33238.
PMID: 39100322
Protein tyrosine phosphatase 1B (PTP1B) is a promising drug target for treating type 2 diabetes (T2DM) and obesity. As a result, developing new therapies that target PTP1B is an attractive...
4.
Rodriguez-Villar K, Cortes-Benitez F, Palacios-Espinosa J, Perez-Villanueva J
Mol Inform
. 2023 Dec;
43(2):e202300206.
PMID: 38095132
Fungal infections caused by Candida are still a public health concern. Particularly, the resistance to traditional chemotherapeutic agents is a major issue that requires efforts to develop new therapies. One...
5.
Alvarez-Almazan S, Solis-Dominguez L, Duperou-Luna P, Fuerte-Gomez T, Gonzalez-Andrade M, Aranda-Barradas M, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628991
Type 2 diabetes (T2D) is one of the most common diseases and the 8th leading cause of death worldwide. Individuals with T2D are at risk for several health complications that...
6.
Olascoaga-Del Angel K, Gutierrez H, Konigsberg M, Perez-Villanueva J, Lopez-Diazguerrero N
Biogerontology
. 2022 Jul;
23(4):453-471.
PMID: 35781578
Senescent cells accumulate within tissues during aging and secrete an array of pro-inflammatory molecules known as senescent-associated secretory phenotype (SASP), which contribute to the appearance and progression of various chronic...
7.
Figueroa-DePaz Y, Perez-Villanueva J, Soria-Arteche O, Martinez-Otero D, Gomez-Vidales V, Ortiz-Frade L, et al.
Molecules
. 2022 Jun;
27(11).
PMID: 35684441
Casiopeinas are a family of copper(II) coordination compounds that have shown an important antineoplastic effect and low toxicity in normal cells. These compounds induce death cells by apoptosis through a...
8.
Perez-Villanueva J, Matadamas-Martinez F, Yepez-Mulia L, Perez-Koldenkova V, Leyte-Lugo M, Rodriguez-Villar K, et al.
Pharmaceuticals (Basel)
. 2021 Aug;
14(8).
PMID: 34451912
Cancer is the second leading cause of death, after cardiovascular diseases. Different strategies have been developed to treat cancer; however, chemotherapy with cytotoxic agents is still the most widely used...
9.
De-la-Cruz-Martinez L, Duran-Becerra C, Gonzalez-Andrade M, Paez-Franco J, German-Acacio J, Espinosa-Chavez J, et al.
Molecules
. 2021 Jul;
26(14).
PMID: 34299651
Regulating insulin and leptin levels using a protein tyrosine phosphatase 1B (PTP1B) inhibitor is an attractive strategy to treat diabetes and obesity. Glycyrrhetinic acid (GA), a triterpenoid, may weakly inhibit...
10.
Rodriguez-Villar K, Yepez-Mulia L, Cortes-Gines M, Aguilera-Perdomo J, Quintana-Salazar E, Olascoaga Del Angel K, et al.
Molecules
. 2021 Apr;
26(8).
PMID: 33917871
Indazole is an important scaffold in medicinal chemistry. At present, the progress on synthetic methodologies has allowed the preparation of several new indazole derivatives with interesting pharmacological properties. Particularly, the...