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Jai Prakash Mehta

Explore the profile of Jai Prakash Mehta including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 142
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Recent Articles
1.
Vo T, McNeela E, ODonovan O, Rani S, Mehta J
Cancers (Basel) . 2024 Dec; 16(23). PMID: 39682150
Background: HER2-positive breast cancer is an aggressive subtype where innate/acquired resistance to targeted drugs remains a challenge. This study aims to uncover the underlying mechanisms of HER2 drug resistance through...
2.
Vo T, El-Sherbieny Abdelaal E, Jordan E, ODonovan O, McNeela E, Mehta J, et al.
Biochem Biophys Rep . 2023 Dec; 37:101588. PMID: 38088952
Breast cancer is the most common type of lethal cancer in women globally. Women have a 1 in 8 chance of developing breast cancer in their lifetime. Among the four...
3.
Pulavarty A, Singh A, Smyth D, Mehta J, Horgan K, Kakouli-Duarte T
Front Plant Sci . 2022 Oct; 13:987059. PMID: 36275579
Potato cyst nematodes (PCN) cause an overall 9% yield loss of total potato production worldwide. Research on sustainable management of PCN is still under progress. Two microbial fermentation products (MFPs)...
4.
Duffy D, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, et al.
Oncotarget . 2015 Dec; 6(41):43182-201. PMID: 26673823
Despite intensive study, many mysteries remain about the MYCN oncogene's functions. Here we focus on MYCN's role in neuroblastoma, the most common extracranial childhood cancer. MYCN gene amplification occurs in...
5.
Mehta J
Methods Mol Biol . 2014 Jul; 1182:93-103. PMID: 25055904
Small RNAs are important transcriptional regulators within cells. With the advent of powerful Next Generation Sequencing platforms, sequencing small RNAs seems to be an obvious choice to understand their expression...
6.
Mehta J, Rani S
Methods Mol Biol . 2011 Sep; 784:41-53. PMID: 21898212
A typical microarray experiment results in series of images, depending on the experimental design and number of samples. Software analyses the images to obtain the intensity at each spot and...
7.
Mehta J
Methods Mol Biol . 2011 Sep; 784:27-40. PMID: 21898211
Microarray technology has made it possible to quantify gene expression of thousands of genes in a single experiment. With the technological advancement, it is now possible to quantify expression of...
8.
Rani S, Mehta J, Barron N, Doolan P, Jeppesen P, Clynes M, et al.
Cell Physiol Biochem . 2010 Jun; 25(6):667-74. PMID: 20511712
Background And Aims: Recently, thioredoxin-interacting protein (Txnip) expression has been implicated in a number of cellular events associated with diabetes, with increased Txnip levels associated with reduced glucose uptake into...
9.
ODriscoll L, Kenny E, Mehta J, Doolan P, Joyce H, Gammell P, et al.
Cancer Genomics Proteomics . 2008 May; 5(2):94-104. PMID: 18460738
Background: Previous studies, by ourselves and others, have indicated that gene transcripts are detectable extracellularly. Advancing on this work, in order to investigate the feasibility of analysing global gene expression...
10.
Martinez V, Kennedy S, Doolan P, Gammell P, Joyce H, Kenny E, et al.
Breast Cancer Res Treat . 2007 Sep; 110(3):521-30. PMID: 17899366
The complex role of drug metabolism-related enzymes and their possible influence in cancer development, treatment and outcome has not yet been completely elucidated. There is evidence that these enzymes can...