Jacqueline E van Muijlwijk-Koezen
Overview
Explore the profile of Jacqueline E van Muijlwijk-Koezen including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
55
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Recent Articles
11.
Edink E, Akdemir A, Jansen C, van Elk R, Zuiderveld O, de Kanter F, et al.
Bioorg Med Chem Lett
. 2012 Jan;
22(3):1448-54.
PMID: 22243960
Using structure-based optimization procedures on in silico hits, dibenzosuberyl- and benzoate substituted tropines were designed as ligands for acetylcholine-binding protein (AChBP). This protein is a homolog to the ligand binding...
12.
Verheij M, de Graaf C, De Kloe G, Nijmeijer S, Vischer H, Smits R, et al.
Bioorg Med Chem Lett
. 2011 Jul;
21(18):5460-4.
PMID: 21782429
A fragment library was screened against the G protein-coupled histamine H(4) receptor (H(4)R) and the ligand-gated ion channel serotonin 5-HT(3A) (5-HT(3A)R). Interestingly, significant overlap was found between H(4)R and 5-HT(3A)R...
13.
De Kloe G, Retra K, Geitmann M, Kallblad P, Nahar T, van Elk R, et al.
J Med Chem
. 2010 Sep;
53(19):7192-201.
PMID: 20828128
The soluble acetylcholine binding protein (AChBP) is a homologue of the ligand-binding domain of the nicotinic acetylcholine receptors (nAChR). To guide future fragment-screening using surface plasmon resonance (SPR) biosensor technology...