Jacobien von Frijtag Drabbe Kunzel
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Explore the profile of Jacobien von Frijtag Drabbe Kunzel including associated specialties, affiliations and a list of published articles.
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4
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44
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Recent Articles
1.
Goblyos A, Santiago S, Pietra D, Mulder-Krieger T, von Frijtag Drabbe Kunzel J, Brussee J, et al.
Bioorg Med Chem
. 2005 Feb;
13(6):2079-87.
PMID: 15727861
A number of 2-aminothiazoles (2a-e) and their amide derivatives (4-10) were prepared. The 2-aminothiazoles themselves were tested as allosteric enhancers of agonist binding to human adenosine A(1) receptors. In a...
2.
Wittendorp M, von Frijtag Drabbe Kunzel J, IJzerman A, Boddeke H, Biber K
Eur J Pharmacol
. 2004 Mar;
487(1-3):73-9.
PMID: 15033378
The adenosinergic system is involved in many important physiological functions. Adenosine exerts its extracellular effects through four types of G-protein-coupled receptors: A(1), A(2A), A(2B) and A(3). Adenosine acts as an...
3.
van Tilburg E, Gremmen M, von Frijtag Drabbe Kunzel J, de Groote M, Ijzerman A
Bioorg Med Chem
. 2003 Apr;
11(10):2183-92.
PMID: 12713828
Novel 2,8-disubstituted adenosine derivatives were synthesized in good overall yields starting from 2-iodoadenosine. Binding affinities were determined for rat adenosine A(1) and A(2A) receptors and human A(3) receptors. Some compounds...
4.
van Tilburg E, von Frijtag Drabbe Kunzel J, de Groote M, Ijzerman A
J Med Chem
. 2002 Jan;
45(2):420-9.
PMID: 11784146
Novel 2,5'-disubstituted adenosine derivatives were synthesized in good overall yields starting from commercially available guanosine. Binding affinities were determined for rat adenosine A(1) and A(2A) receptors and human A(3) receptors....