Jacob Hudobenko
Overview
Explore the profile of Jacob Hudobenko including associated specialties, affiliations and a list of published articles.
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10
Citations
195
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0
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Recent Articles
1.
Hudobenko J, Di Gesu C, Mooz P, Petrosino J, Putluri N, Ganesh B, et al.
Mol Psychiatry
. 2024 Oct;
PMID: 39443733
Advanced maternal age (AMA) is defined as a pregnancy in a woman older than 35 years of age. AMA increases the risk for both maternal and neonatal complications, including miscarriage...
2.
Hudobenko J, Gayen M, Benoit M, Singh N, Yan R
Neural Regen Res
. 2023 Jul;
18(12):2667-2668.
PMID: 37449614
No abstract available.
3.
Zhou J, Singh N, Galske J, Hudobenko J, Hu X, Yan R
Mol Neurodegener
. 2023 May;
18(1):31.
PMID: 37143090
Background: Abnormal accumulation of amyloid beta peptide (Aβ) in the brain induces a cascade of pathological changes in Alzheimer's disease (AD), and inhibiting BACE1, which is required for Aβ generation,...
4.
Gayen M, Benoit M, Fan Q, Hudobenko J, Yan R
J Biol Chem
. 2022 Sep;
298(11):102532.
PMID: 36162508
CX3CL1, also known as fractalkine, is best known for its signaling activity through interactions with its cognate receptor CX3CR1. However, its intrinsic function that is independent of interaction with CX3CR1...
5.
Marino Lee S, Hudobenko J, McCullough L, Chauhan A
Exp Neurol
. 2020 Nov;
336:113530.
PMID: 33221396
Microglia are one of the first responders to ischemic injury. Aged microglia acquire a senescent phenotype and produce more inflammatory cytokines after stroke. Depletion of microglia in young mice worsens...
6.
Lee J, Venna V, Durgan D, Shi H, Hudobenko J, Putluri N, et al.
Gut Microbes
. 2020 Sep;
12(1):1-14.
PMID: 32897773
Aging is associated with cognitive decline and decreased concentrations of short-chain fatty acids (SCFAs) in the gut. SCFAs are significant in that they are protective to the gut and other...
7.
Honarpisheh P, Blixt F, Blasco Conesa M, Won W, dAigle J, Munshi Y, et al.
Brain Behav Immun
. 2020 Aug;
90:235-247.
PMID: 32861719
Aging is associated with dysfunction of the gut microbiota-immune-brain axis, a major regulatory axis in both brain health and in central nervous system (CNS) diseases. Antigen presenting cells (APCs) play...
8.
Hudobenko J, Ganesh B, Jiang J, Mohan E, Lee S, Sheth S, et al.
Aging (Albany NY)
. 2020 May;
12(9):8049-8066.
PMID: 32365331
Growth differentiation factor (GDF) 11 levels decline with aging. The age-related loss of GDF 11 has been implicated in the pathogenesis of a variety of age-related diseases. GDF11 supplementation reversed...
9.
Chauhan A, Hudobenko J, Al Mamun A, Koellhoffer E, Patrizz A, Ritzel R, et al.
J Neuroinflammation
. 2018 May;
15(1):148.
PMID: 29776451
Background: Activation of transforming growth factor-β-activated kinase 1 (TAK1) occurs after stroke and leads to an exacerbation of brain injury. TAK1 is involved in innate and adaptive immune responses, but...
10.
Verma R, Cronin C, Hudobenko J, Venna V, McCullough L, Liang B
Brain Behav Immun
. 2017 Jul;
66:302-312.
PMID: 28751018
Introduction: Acute ischemic injury leads to severe neuronal loss. One of the key mechanisms responsible for this effect is inflammation, which is characterized by the activation of myeloid cells, including...